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Rungta Institute of Pharmaceutical Sciences
The study evaluates the quality and consistency of various marketed brands of Amoxicillin capsules/tablets using UV spectroscopy. The objective is to determine the actual drug content in comparison to the labelled claim and assess any significant variability among the brands, which may influence therapeutic efficacy.
Amoxicillin, a widely used β-lactam antibiotic, is available under numerous brand names. Despite regulatory standards, variations in drug content among brands can impact patient outcomes. UV spectrophotometry is a simple, cost-effective, and reliable method for quantifying drug content.
Fig: - Amoxicillin 250mg
Amoxicillin is available in the dosage form of Tablets, Capsules, Suspensions, Cream, Lotions, Ointments etc. & some combination brands.
List of Combination Brands of Amoxicillin: -
1.Amoxicillin + Clavulanic Acid Combination Brands: -
|
Brand Name |
Formulation |
Strength (Amox + Clav) |
Manufacturer |
|
Augmentin |
Tablet |
500 + 125 mg / 875 + 125 mg |
GlaxoSmithKline (GSK) |
|
Clavam |
Tablet |
500 + 125 mg / 625 mg |
Alkem |
|
Moxclav |
Tablet |
500 + 125 mg |
Sun Pharma |
|
Clavamox |
Tablet / Capsule |
250 + 125 mg / 500 + 125 mg |
Pfizer |
|
Curam |
Tablet / Capsule |
500 + 125 mg |
Sandoz (Novartis) |
|
Amoxyclav |
Tablet |
625 mg |
Cipla |
|
Duomox-CV |
Tablet |
500 + 125 mg |
German Remedies |
2. Amoxicillin + Clavulanic Acid (Clavulanate Potassium): -
|
Brand Name |
Formulation |
Strength (Amox + Clav) |
Manufacturer |
|
Augmentin |
Tablet/Capsule |
500 + 125 mg / 875 + 125 mg |
GSK |
|
Clavam |
Tablet |
500 + 125 mg / 625 mg |
Alkem |
|
Moxclav |
Reference
Ayushi Khadatkar, Nitin Kurrey, Suman Sahu, Shobha Sahu*, Comparative Study of Different Brands of Amoxicillin Using UV Spectroscopy, Int. J. Sci. R. Tech., 2025, 2 (6), 382-385. https://doi.org/10.5281/zenodo.15632247 More related articlesA Literature Review on Drugs Associated with Liver...Dony D., Jackson Selvin Y., Silambarasan M., Balaji S....Consumer Decision Making In Residential Constructi...S. Elavarasan, M. Yasmin Regina...Comparative Analysis of the Efficiency and Safety ...Arnab Roy, Abhinav Kumar, Shivam Kashyap, Ayush Kumar Verma , Sha...Comparative Analysis Of Financial Performance Of Kerala-Based Private Sector Ban...Mohith Jayan, Somasekharan T. M....Comparative Study of UV And HPLC Methods for Estimation of Drug...Sarthak Sanap, Sakshi Tarle...
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10.5281/zenodo.15632247