Pituk Swapnanjali *
Patil Sanika
Both Singh et al. (2016) and Barhoi et al. (2021) agree that cancer is a main health concern. [1] Its distinguishing characteristic is the rapid proliferation of cells that evades cell cycle checkpoints. Even though cancer biology is advancing at a rapid pace, the cancer incidence and mortality rate are still going up. [3] These diagnostic methods, unfortunately, failed to yield the desired outcomes. Further complications associated with these treatments include cancer recurrence, non-target organ harm, and drug resistance (Choudhari et al., 2020). In order to fight this deadly disease, scientists are continuously seeking out novel anticancer medicines that show promise, ideally with better efficacy and less side effects [7]. To skilfully evade cell death by apoptosis, cancer cells accumulate a number of genetic and epigenetic changes (Klein, 2004). The development of anticancer chemotherapeutics may thus depend on substances that may induce cell death in cancer cells (Lee, 1999). [8] Several cancer treatments derived from plants account for about 75% of the total (Craig, 1999). [9] Surprisingly, essential oils, which are widely distributed in nature, have never been used for their anticancer properties while being widely used in aromatherapy, perfumery, food and flavoring, and other fields. It is generally known that several essential oils or their components have strong antibacterial and antifungal properties. [10] Asteraceae family includes the genus Tagetes, which has 56 species, including 29 perennials and 27 annuals. Around the world, Tagetes sp. are cultivated as multipurpose plants, with the most popular species being T. minuta, T. erecta, T. patula, and T. tenuifolia (Vasudevan et al., 1997). [11] Folk medicine has utilized Tagetes sp. to treat stomach and intestinal disorders. Carotenoids, which are utilized as food coloring and feed additives, are among the highly intriguing biologically active chemicals that come from this species.and having antiaging and anticancer benefits (Block et al., 1992), flavonoids with pharmacological qualities (Tereschuk et al., 1997), and essential oils with antibacterial and insecticidal qualities (Piscaglia et al., 1996). T. minuta L. volatile oils have a suppressive biological action and are utilized as food flavorings and perfumes (Chamorro et al., 2008), as well as antibacterial agents (Senatore et al., 2004). in opposition to certain diseases and insects (Vasudevan et al., 1997). The Lamiaceae family includes the genus Ocimum. [12] When it comes to cancer-related deaths, pancreatic cancer is second to none in the world. in [13] Chronic pancreatitis, obesity, heavy alcohol use, cigarette smoking, and a diet rich in red meat are some of the risk factors for pancreatic cancer. [14] Because there are no symptoms of the disease, pancreatic cancer is frequently discovered in its advanced stages. [15] Surgery is still the most effective treatment, although as previously said, the patient's chances of survival are low. [16] The next step is radiation and chemotherapy. [17] The herb is used to treat the common cold, bronchitis, and the common cold. The leaves' juice is used to make sarache. [18-19] The roots' extract is used as a laxative. Traditionally, Tagetes erecta and Tagetes patula leaf juice has been utilized as an antimalarial and antipyretic. Tagetes minuta has a potent larvicidal activity and has long been used to ward off mosquitoes. [20] Tagetes patula juice is used to treat cuts and wounds because it contains iodine. Its floral juice is used as a carminative. In addition to being utilized in food, Tagetes lucida is also used to scent bath water with its leaves and flower heads. [21] Traditional Mexican teas made from Tagetes lucida and Tagetes filifolia shoots are popular beverages and natural cures for indigestion and colic. In the perfumery industry, Tagetes minuta oil is well-liked due to its powerful and piercing scent. Terpenoids, thiophenes, flavonoids, carotenoids, and phenolic chemicals are found in Tagetes species [22] The herbaceous genus Tagetes includes over fifty species of annual and perennial plants belonging to the Compositae and Asteraceae families. Genda Phool (Marigold) is the local name for Tagetes erecta L. Indian marigolds are a traditional spice. [23] The A foundational ingredient in the majority of Indian curries, marigold is a flavor-enhancing spice. Using marigolds in curry dishes has a history that spans over five thousand years. [24] The tall, branching plant originally hails from Mexico and other warmer regions of the United States but has since been eradicated from the subtropics and tropics, including Bangladesh and India. [25]
10.5281/zenodo.15324127