Abstract
The mulberry (Morius alba), which is a member of the Moraceae family, is a symbol of fruit coldness. It comes in three different colours: white, red, and black. Its fruits have a variety of therapeutic benefits, including antioxidant, anticancer, antidiabetic, hepatoprotective, neuroprotective, anti-inflammatory, anti-obesity, hypolipidemic, and antibacterial qualities. Their nutritional makeup and phytochemical-mediated biological pathways further bolster their significance. Although there are many different species of mulberries, the review focusses on Morus alba, Morus nigra, and Morus rubra, whose precise roles in biological systems are still not well understood. It also highlights recent developments in our understanding of their pharmacological properties, emphasising their relevance in therapeutic applications.
Keywords
Mulberry, Therapeutic Benefits, Nutritional Composition, Phytochemical-Mediated
Introduction
The therapeutic properties of Morusalba L. leaves, whose Latin name is derived from Folium Mori, are found in the Han dynasty more than 2,000 years ago, and are recorded in the Shennog Materia Medica. The dried Chinese name for these leaves is Sangye. Subsequently, Li Shizhen in the Ming Dynasty supplied mulberry leaves in the book of Compediun of Materia Medica, which listed the benefits of detoxifying, dispelling harmful winds, promoting blood circulation, and easing stasis. [1.2.3] A woody perennial plant, mulberries are native to China. It belongs to the Moraceae family and grows in a variety of climates, including tropical and subtropical ones. It is used in Chinese and Indian medicine for the most part, and in Japan, mulberry leaves are used to make tea and juice powder. It will be shown that it contains steroids, flavonoids, amino acids, vitamins, triterpenes, and other trace elements. It has many species, including Morus laevigatta, Morus rubra, Morus nigra, and Morus alba. Its roots, leaves, bark, stem twigs, and fruits contain valuable bioactive constituents, and its black and red varieties are known for their beneficial effects on the human body. Mulberry varieties are Unani and acknowledged in Ayurveda and Chinese medicine [4,5]. In Unani medicine is known as Tutiaswad & Indian mulberry is known as it grow in Kalpa Vruksha 24 40 28°C May through June is India's ideal growth season in terms of temperature. The physiological and biochemical roles of various molecular weight peptides generated from various plants have been extensively studied, but little is known about the oligopeptides' potential as antidiabetic and antioxidant medicines. High-performance liquid chromatography (HPLC) and protein sequencers will be used in this work to separate and characterise oligopeptides from different mulberry cultivars. Additionally, the target peptides' in vitro antioxidant and antidiabetic activities will be assessed. Substrates or byproducts of the breakdown of primary metabolites are the source of secondary metabolites. Substances known as secondary metabolites are found in minimal amounts yet are just as crucial to the basic physiological processes of plants. [6,7]. Fig.No.01 & 02
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Safid Halim Khan
Corresponding author
Department of Pharmacy, Siddhi’s Institute of Pharmacy, Nandgaon, DBATU University, Raigad, Lonere-421401
Prachi Desale
Co-author
Department of Pharmacy, Siddhi’s Institute of Pharmacy, Nandgaon, DBATU University, Raigad, Lonere-421401
Vivek Waghere
Co-author
Department of Pharmacy, Siddhi’s Institute of Pharmacy, Nandgaon, DBATU University, Raigad, Lonere-421401
Prachi Desale, Safid Halim Khan*, Vivek Waghere, A Fruit Review on Marvelous Milberry With Its Nutrition, Pharmacological Activity and Formulation, Int. J. Sci. R. Tech., 2025, 2 (5), 472-485. https://doi.org/10.5281/zenodo.15469183
10.5281/zenodo.15469183
