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Abstract

Urticaria is a frequent dermatological condition affecting approximately 15–25% of individuals at some point in their lives. This condition tends to be more common in adult than in children. It is marked by the sudden appearance of itchy, raised skin lesions. As conventional treatment focuses on antihistamines and corticosteroids, recurrence and chronicity remain challenging. Ayurveda offers alternative approach aimed at managing root cause through dosha balancing and detoxification. This case report presents a 57-year-old male with a 3-month history of recurrent, itchy, round, reddish rashes over face, neck, bilateral arms and legs. Episodes occurred daily and were partially relieved by over-the counter antihistamines. Based on Ayurveda principles, the condition was diagnosed as Utkota, marked by circular, itchy, reddish, numerous and recurrent lesions with predominance of Kapha dosha. Management included Shodhana chikitsa (Vamana) followed by Shamana chikitsa. Additionally, dietary modifications and lifestyle advice were given to avoid Nidana (triggering factors). The patient showed complete resolution of symptoms in 10 days. No recurrence was reported during a 15 day follow up. This case highlights the effectiveness of Ayurvedic management in urticaria.

Keywords

Urticaria, Utkota, Ayurveda, Shodhana, Vamana

Introduction

Urticaria, commonly known as hives, is a frequent dermatological condition affecting approximately 15–25% of individuals at some point in their lives. It is marked by the sudden appearance of itchy, raised skin lesions known as wheals. These lesions are typically pink to red, often with a pale center, and can vary in size from a few millimeters to several centimeters. Characteristically transient, the wheals usually resolve within 48 hours without leaving any trace.1 Urticaria is broadly classified into two categories: acute and chronic. Acute urticaria is defined by the presence of lesions lasting less than six weeks, while chronic urticaria is characterized by the recurrence of lesions for more than six weeks, typically appearing on most days of the week.2 The pathogenesis of urticaria involves the activation of mast cells and the release of inflammatory mediators. In acute urticaria, an IgE-mediated hypersensitivity reaction leads to mast cell degranulation, primarily releasing histamine, which causes the characteristic transient erythema and edema. Mast cells require time to replenish their granules, explaining why lesions do not recur immediately in the same area. In contrast, chronic urticaria often involves antigens binding to high-affinity IgE receptors on mast cells and basophils, triggering repeated degranulation. Autoimmune mechanisms also play a significant role, with pre-existing IgE antibodies facilitating a more rapid allergic response upon subsequent antigen exposure.3The recurrent and unpredictable nature of urticaria can significantly impact quality of life, making an understanding of its presentation and management essential. In Ayurveda, Urticaria fits in to either of Sheetapitta, Udarda, Kota or Utkota based on the difference in lakshanas mentioned in classics.  In the present case study, the symptoms aligned with the diagnosis of Utkota, marked by circular, itchy, reddish, numerous, recurrent lesions and the condition was effectively managed through Shodhana followed by Shamana treatment.

CASE REPORT

Details of the case

A 57year old man, presented in the Outpatient department of Visha Chikitsa at Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital, Hassan in the month of July with complaints of recurrent, itchy, raised round reddish rashes over face, neck, bilateral arms and legs since last 3 months.

History of present illness:

Patient was apparently normal 3 months back. Later after being exposed to construction works at his home, he noticed development of raised round rashes over different parts of the body associated with itching, which subsided on its own. He ignored the condition for nearly one and half months. Later, the condition became severe and was found not subsiding itself. On consultation he was diagnosed with Urticaria by the physician and advised to take Bilastine. Symptoms were found to reappear on discontinuation of medicine. So, he approached our hospital for better management.

History of past illness:

No history of Diabetes, Hypertension or any other metabolic disorders.

Family history: Nothing significant

Personal history

Diet – Mixed

Appetite- Good

Bowel- Regular

Micturition- Regular

Sleep- Disturbed

General Examination

There was no evidence of pallor, edema, clubbing, cyanosis, icterus, or lymphadenopathy on general physical examination.

Vital Signs

Pulse: 74/min

Blood Pressure: 120/70mmHg

Respiratory Rate: 16/min

Temperature: 97 F

Weight: 84kg

Height: 174cm

Systemic examination

Central nervous system, cardiovascular system, respiratory system and gastrointestinal system examinations show no abnormality.

Integumentary system 

Distribution- Generalized  

Number of lesions – Multiple

Pattern – Discrete; later confluent

Areas involved – Trunk, limbs, face

Local examination (Representative lesion)

Site- Right Upper limb

Size- 3 × 2 cm

Shape- Oval

Surface- Smooth

Margins- Well defined

Color- Pink to red

Dermographism - Positive

Asta-Vidha Pareeksha:

Nadi: Vata pitta

Mala: Prakruta

Mutra: Prakruta

Jihwa: Alipta

Shabda: Spashta

Sparsha: Anushna-Sheeta

Drik: Prakruta

Akriti: Madhyama

Dashavidha pareeksha

Prakruti: Pitta Vata

Vikruti: Kapha Vata

Saara: Madhyama

Samhanana: Madhyama 

Pramana: Madhyama

Satva: Madhyama

Satmya: Madhura Katu

Aharashakti: Madhyama

Vyayama shakti: Madhyama

Vaya: Madhyama

Investigations

Allergic test suggested that he is allergic to ethylene anhydride, dust mite, house dust, chili, pepper, curd, yeast, lemon, pea, eggplant, peanut, lentil, grape and common reed. Lipid Profile - Triglycerides- 204.1mg/dl, VLDL cholesterol – 40.8 mg/dl. All other reports were within normal limit.

Therapeutic Intervention

Initially, proper Ama pachana and Agni deepana was done on OPD basis and on first two days of admission with Bilwadi Gutika and Gandaka rasayana. It was followed by Snehapana for 5 days with Panchatiktaka Guggulu Grita with a starting dose of 30 ml to 220 ml on the last day. Sarvanga Abhyanga with Marichadi taila followed by Bashpa sweda was done for one day during visrama kala and Vamana (emesis therapy) was conducted with Madanaphala pippali, Vacha, Yashtimadhu, Saindava, Pippali, Honey. Diet advised during the course of treatment was Mudga yusha, Kichdi, Ganji.

Discharge medicines

  1. Bilwadi gutika 1-0-1 A/F
  2. Guduchi capsule 2-0-0 B/F
  3. Avipathikara churna 5gm at night B/F
  4. Marichadi taila E/A

On Follow UP (After 15 days)

  1. Bilwadi gutika 1-0-1 A/F
  2. Guduchi capsule 2-0-0 B/F
  3. Avipathikara churna 5gm at night B/F
  4. Marichadi taila E/A

OBSERVATIONS AND RESULTS

Sl No.

Symptoms

Before treatment

After treatment

  1.  

Itching

+ + +

-

  1.  

Raised reddish round rashes

+ + +

-

 

Before

After

DISCUSSION

Understanding Urticaria

Urticaria is a skin disorder marked by red, swollen, and itchy wheals, primarily caused by mast cell activation and the release of histamine. In acute cases, this is often triggered by an IgE-mediated allergic reaction, which increases vascular permeability, leading to the typical wheal and flare appearance. Interestingly, lesions rarely recur at the same site immediately, as mast cells require time to replenish their granules. Chronic urticaria, however, involves more complex mechanisms. It may result from continuous activation of mast cells and basophils, sometimes due to autoimmune processes where antibodies target IgE or its receptors. Standard treatment includes H1 antihistamines, but many patients experience persistent symptoms despite high doses. Corticosteroids are used in resistant cases but can cause risks with long-term use. Biologic therapies like omalizumab (an anti-IgE monoclonal antibody) offer newer options but are costly and not always effective. Symptoms frequently return after stopping treatment, indicating a need for alternative, holistic approaches.4

Ayurvedic Perspective  

In Ayurveda, Urticaria fits in to either of Sheetapitta, Udarda, Kota or Utkota based on the difference in lakshanas mentioned in classics. Both Sheetapitta and Udarda presents with swelling over the skin resembling that produced by the sting of wasp, associated with itching, pricking pain, vomiting, fever and burning sensation. They are distinguished by the difference in dosha predominance, where Sheetapitta is Vata predominant and Udarda is Kapha predominant.5 Skin manifestations which are circular, itchy, reddish and numerous are considered as Kota; and if these complaints occur recurrently, it is called as Utkota.6 In the commentary it is mentioned that Kota is developed from Udarda implying that Kota and Utkota is Kapha dosha predominant. In the present case study, as the patient presents with circular, reddish, numerous, recurrent lesions with severe itching indicating the predominance of Kapha dosha, the condition was diagnosed as Utkota.

Principle Behind Each Intervention

  1. Ama Pachana and Agni Deepana

Management was initiated with a focus on Ama Pachana and Agni Deepana, as these are considered essential preparatory steps before undertaking Shodhana (Purification therapy). Bilwadi Gutika was administered, as it is indicated in ajeerna condition and most of its drugs pacify both Kapha and Vata doshas7. Additionally, Gandaka Rasayana was prescribed due to its direct indication in strengthening agni (digestive fire) along with effect on Kandu (itching) and Kushta (skin diseases).8 Together, these formulations served in Ama Pachana and correcting Agni, thereby preparing the body for shodhana procedure

  1. Snehapana with Panchatikta Guggulu Ghrita

Snehapana was employed as a preparatory procedure before Vamana. As Kapha shamana was a main intention in the treatment, and as tikta rasa drugs are best suited for it, Panchatiktaka Guggulu grita was chosen for Snehapana considering its indication in twak vikara and kandugna action9. The progression of the Snehapana dosage starting from 30 ml on the first day and gradually escalating up to 220 ml by the fifth day allowed for proper assessment of snigda lakshana, such as improvement in digestion, clarity of belching, softness of body tissues and unctuous stools, indicating readiness for the next stage of Panchakarma.

  1. Abhyanga and Swedana

Abhyanga (oil massage) and Swedana (fomentation) are essential preparatory procedures prior to administering Vamana. This procedure aims to loosen and mobilize the vitiated doshas, especially Kapha, towards the gastrointestinal tract, facilitating their effective elimination during Vamana. In this case Marichadi taila was selected for external application because of its indication in kandu, kushta and kapha vata hara action10. Bashpa sweda administered following Abhyanga helps in dosha vilayana and promotes movement of vitiated doshas from sakha to koshta.

  1. Vamana

The patient underwent Vamana Karma, as it is the principal Shodhana therapy indicated for Kapha dominant disorders. It aimed at root-level elimination of vitiated Kapha, which is considered the primary dosha involved in the Utkota. As most of the recurrent lesions were jatru urdwa, this shodhana procedure was the best of choice.

  1. Shamana Chikitsa

After shodhana, shamana chikitsa is essential to prevent recurrence. Bilwadi gutika and Avipathikara churna helps in seshadosha harana (removal of residual vitiated doshas). Guduchi capsule was given focusing on the Kushtagna11 and rejuvenative action of guduchi and Marichadi taila helps in managing local symptoms like itching.

Dietary and Lifestyle Management

Easily digestible and non-irritating preparations such as Mudga Yusha (green gram soup), Khichdi (rice and lentil porridge), and Ganji (rice gruel) were recommended. These foods are light, nourishing yet non-aggravating, making them ideal for digestive balance. Along with dietary guidelines, specific lifestyle recommendations were provided to avoid Nidanas (triggering factors), which are crucial in preventing recurrence. The patient was advised to avoid exposure to known allergens, sudden temperature variations, emotional stress, and incompatible food combinations, all of which are known to disrupt dosha equilibrium and contribute to the pathogenesis of urticaria.

By identifying and eliminating individual-specific triggers and promoting a supportive diet and routine, the likelihood of recurrence is significantly minimized, as evidenced in this case.

CONCLUSION

This case report demonstrates the effectiveness of Ayurvedic management in addressing recurrent urticaria through a holistic approach that targets the root cause rather than just symptomatic relief. The diagnosis of Utkota, based on classical Ayurvedic texts, allowed for a personalized treatment plan involving Shodhana Chikitsa (Vamana) followed by Shamana Chikitsa, along with dietary and lifestyle modifications to eliminate Nidana (triggers). The patient experienced complete resolution of symptoms within 10 days, with no recurrence during the 15-day follow-up period. This highlights the holistic approach of Ayurveda in managing dermatological conditions like urticaria, emphasizing dosha balance and detoxification. Further studies with larger sample sizes are needed to validate these findings and explore Ayurveda's broader role in managing chronic skin disorders.

REFERENCE

  1. Kanani A, Schellenberg R, Warrington R. Urticaria and angioedema. Allergy Asthma Clin Immunol. 2011 Nov 10;7 Suppl 1(Suppl 1): S9. doi: 10.1186/1710-1492-7-S1-S9. PMID: 22165855; PMCID: PMC3245442.  
  2. Kanani A, Schellenberg R, Warrington R. Urticaria and angioedema. Allergy Asthma Clin Immunol. 2011 Nov 10;7 Suppl 1(Suppl 1): S9. doi: 10.1186/1710-1492-7-S1-S9. PMID: 22165855; PMCID: PMC3245442.
  3. Kayiran MA, Akdeniz N. Diagnosis and treatment of urticaria in primary care. North Clin Istanb. 2019 Feb 14;6(1):93-99. doi: 10.14744/nci.2018.75010. PMID: 31180381; PMCID: PMC6526977.
  4. Asero R, Pinter E, Marra AM, Tedeschi A, Cugno M, Marzano AV. Current challenges and controversies in the management of chronic spontaneous urticaria. Expert Rev Clin Immunol. 2015;11(10):1073-82. doi: 10.1586/1744666X.2015.1069708. Epub 2015 Jul 15. PMID: 26174347.
  5. Vachaspati Vaidya. Madhava Nidana. Edited by Jadavji Tricumji Acharya Vaidya. 6th ed. Varanasi: Chaukambha Orientalia; 2001. Chapter 50, p. 290.
  6. Vachaspati Vaidya. Madhava Nidana. Edited by Jadavji Tricumji Acharya Vaidya. 6th ed. Varanasi: Chaukambha Orientalia; 2001. Chapter 50, p. 291.
  7. Shubha PU, Honwad SV, Ballal SR. A review on Bilwadi Gutika. Int Ayurved Med J. 2017 Feb;5(2):435–439.
  8. Yoga Ratnakara. Edited and Translated by Suresh Babu M S. 1st edition. Chawkhamba Sanskrit Series Office. Varanasi. 2008; Uttarardha. Vol II. RasayanaVijnana/28-31. P-1250.
  9. Ranjeetha K, Chaitra H, Anaghashree S. Management of Vaipadika (Palmo Plantar Psoriasis) through Shodhana - A Case Study. World J Pharm Pharm Sci. 2024;13(3) DOI: 10.20959/wjpps20243-26902
  10. Sharma G, editor and translator. Sarngadhara Samhita. Varanasi: Krishnadas Academy; Madhyamakhanda 9/148–152, p. 227.
  11. Srikantha Murthy KR, editor and translator. Susruta Samhita. Vol. 2, Chikitsa Sthana. Varanasi: Chaukhambha Orientalia; 2005. Chapter 10, verse 14, p. 122.

Reference

  1. Kanani A, Schellenberg R, Warrington R. Urticaria and angioedema. Allergy Asthma Clin Immunol. 2011 Nov 10;7 Suppl 1(Suppl 1): S9. doi: 10.1186/1710-1492-7-S1-S9. PMID: 22165855; PMCID: PMC3245442.  
  2. Kanani A, Schellenberg R, Warrington R. Urticaria and angioedema. Allergy Asthma Clin Immunol. 2011 Nov 10;7 Suppl 1(Suppl 1): S9. doi: 10.1186/1710-1492-7-S1-S9. PMID: 22165855; PMCID: PMC3245442.
  3. Kayiran MA, Akdeniz N. Diagnosis and treatment of urticaria in primary care. North Clin Istanb. 2019 Feb 14;6(1):93-99. doi: 10.14744/nci.2018.75010. PMID: 31180381; PMCID: PMC6526977.
  4. Asero R, Pinter E, Marra AM, Tedeschi A, Cugno M, Marzano AV. Current challenges and controversies in the management of chronic spontaneous urticaria. Expert Rev Clin Immunol. 2015;11(10):1073-82. doi: 10.1586/1744666X.2015.1069708. Epub 2015 Jul 15. PMID: 26174347.
  5. Vachaspati Vaidya. Madhava Nidana. Edited by Jadavji Tricumji Acharya Vaidya. 6th ed. Varanasi: Chaukambha Orientalia; 2001. Chapter 50, p. 290.
  6. Vachaspati Vaidya. Madhava Nidana. Edited by Jadavji Tricumji Acharya Vaidya. 6th ed. Varanasi: Chaukambha Orientalia; 2001. Chapter 50, p. 291.
  7. Shubha PU, Honwad SV, Ballal SR. A review on Bilwadi Gutika. Int Ayurved Med J. 2017 Feb;5(2):435–439.
  8. Yoga Ratnakara. Edited and Translated by Suresh Babu M S. 1st edition. Chawkhamba Sanskrit Series Office. Varanasi. 2008; Uttarardha. Vol II. RasayanaVijnana/28-31. P-1250.
  9. Ranjeetha K, Chaitra H, Anaghashree S. Management of Vaipadika (Palmo Plantar Psoriasis) through Shodhana - A Case Study. World J Pharm Pharm Sci. 2024;13(3) DOI: 10.20959/wjpps20243-26902
  10. Sharma G, editor and translator. Sarngadhara Samhita. Varanasi: Krishnadas Academy; Madhyamakhanda 9/148–152, p. 227.
  11. Srikantha Murthy KR, editor and translator. Susruta Samhita. Vol. 2, Chikitsa Sthana. Varanasi: Chaukhambha Orientalia; 2005. Chapter 10, verse 14, p. 122.

Photo
Neethu M.
Corresponding author

Department of Agada Tantra, Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital, Hassan, Karnataka, India

Photo
Chaitra H.
Co-author

Department of Agada Tantra, Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital, Hassan, Karnataka, India

Photo
Ananya Latha Bhat
Co-author

Department of Agada Tantra, Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital, Hassan, Karnataka, India

Photo
Madhusudhana V.
Co-author

Department of Agada Tantra, Sri Dharmasthala Manjunatheswara College of Ayurveda and Hospital, Hassan, Karnataka, India

Neethu M.*, Chaitra H., Ananya Latha Bhat, Madhusudhana V., Ayurvedic Approach in the Management of Urticaria – A Case Study, Int. J. Sci. R. Tech., 2025, 2 (10), 102-107. https://doi.org/10.5281/zenodo.17294703

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