1MSc Student, Department of Botany, Bioinformatics, Climate Change Impacts Management, Gujarat University, Ahmedabad.
2Research Scholar, Department of Botany, Bioinformatics, Climate Change Impact Management, Gujarat University, Ahmedabad.
3Professor, Department of Botany, Bioinformatics, Climate Change Impact Management, Gujarat University, Ahmedabad.
4Research Scholar, Department of Microbiology and Biotechnology, Gujarat University Ahmedabad.
5Assistent Professor, Department of Microbiology and Biotechnology, Gujarat University, Ahmedabad
Jacquemontia pentanthos (Jacq.) G. Don., also referred to as Sky-blue Cluster vine, comprises a flowering vine that belongs to the Convolvulaceae family. This research focused on the investigation of phytochemical constituents, antioxidant and antibacterial efficacy of the plant parts of J. pentanthos (Jacq.) G. Don. different parts like leaves, stem, and flowers. This research mainly focuses on the investigation of qualitative & quantitative phytochemical screening, antioxidant and anti-bacterial activity of different plant parts. Plant extract was prepared in three solvent like methanol, hexane and distilled water by cold extraction method. From the qualitative phytochemical screening, different extract shows the presence kind of secondary metabolites like alkaloids, flavonoids, phenols, tannins, and phytosterols, and primary metabolites like protein and amino acids. The quantitative assays have been used to identify the total content of phenols, flavonoids, and tannins by using the spectrophotometric method. The antioxidant activity has been determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and phosphomolybdate assay (PMA), which revealed statistical data regarding the plant’s capacity to scavenge free radicals and reduce oxidative stress. Antibacterial activity was determined against two different bacterial strains, including Gram +ve bacteria (Staphylococcus aureus) and Gram -ve bacteria (Escherichia coli), by performing the well diffusion method. The various phytochemical constituents show during the analysis of different plant parts and extraction solution. The highest flavonoid content was found in hexane extract of leaves, with value of 7.265 ± 0.0036. The highest phenolic content was found in methanol extract of flowers, with value of 6.302 ± 0. While the highest tannin content was found in methanol extract of leaves, with value of 2.348 ± 0.042. Hexane flower extract shows higher antioxidant activity with lowest IC50 value of 14.06 in DPPH assay, while hexane stem extract shows less antioxidant activity with highest IC50 value of 88.39 among all the extracts. In PMA antioxidant activity distilled water extracts of flower shows % inhibition of free radicals, with value of 86.06%. The leaf extracts demonstrate high antibacterial potential then the stem. The largest zone of inhibition was seen in fresh leaf methanolic extract 23mm. D.W. extracts not evaluate any zone of inhibition.
Jacquemontia pentanthos (Jacq.) G. Don is a plant of the Convolvulaceae family, which consists of 55 genera and 1650 species found in tropical and temperate locations worldwide. J. pentanthos (Jacq.) G. Don. is a popular decorative plant that grows in tropical and subtropical regions of India (Sultan and Rahman, 2016). J. pentanthos (Jacq.) G. Don. aerial parts were grown in Egypt for the first time, including potential as a natural resource for therapeutic purposes (Eskander et al., 2019). The genus is known for its complexity at the species level, as some species intergrade and can be challenging to identify. There is limited knowledge on their biology and ecology, although it is assumed that they are pollinated by bees or similar insects. The majority of species are modest, twining or trailing, and have beautiful blue blooms. Although the genus has limited economic or ecological significance, some species, such as J. pentanthos (Jacq.) G. Don and J. tamnifolia (L.) griseb, are planted for ornamental purposes (Robertson, 1971).
Meet Dhokiya, Riya Kadia, Nainesh Modi*, Milan Dabhi, Dweipayan Goswami, Bioactive Compounds and Biological Activities of Jacquemontia Pentanthos (Jacq.) G. Don.: A Phytochemical and Pharmacological Study, Int. J. Sci. R. Tech., 2025, 2 (4), 568-582. https://doi.org/10.5281/zenodo.15276538
10.5281/zenodo.15276538
