1Research Scholar, Department of Pharmaceutics, Delight College of Pharmacy, Koregaon Bhima, Pune, Maharashtra. India-412216.
2Assistant Professor Department of Pharmaceutics, Delight College of Pharmacy, Koregaon Bhima, Pune. Maharashtra, India-412216.
3Assistant Professor, Department of Quality Assurance Techniques, Delight College of Pharmacy, Koregaon Bhima, Pune, Maharashtra, India-412216.
In recent years, herbal medicines have attracted considerable interest due to their proven therapeutic benefits and low risk of side effects. This study focuses on the Formulation and Evaluation of Herbal Ointment from Neem and Turmeric Extract. both recognized for their antimicrobial, antioxidant, and anti-inflammatory effects. The extracts were prepared using ethanol as the solvent and then blended into an oil-based ointment following standard pharmaceutical practices. The formulation underwent comprehensive evaluation, including physical characteristics (such as color, texture, spreadability, and pH), stability testing, and antimicrobial effectiveness against Staphylococcus aureus and Escherichia coli. Findings demonstrated that the ointment exhibited good spreadability, an appropriate pH level, and maintained its stability over time. Antimicrobial tests showed significant bacterial inhibition, supporting the traditional use of neem and turmeric in treating wounds and preventing infections. This research highlights the potential of this herbal formulation as a safe and effective natural alternative to conventional topical medications.
For thousands of years, herbal medicines have been an essential component of traditional healthcare systems and continue to serve as a primary healthcare option in many regions worldwide. Herbal ointments semi-solid preparations meant for topical use are particularly valuable in treating various skin conditions, including infections, wounds, inflammations, and burns. These formulations are favored not just for their medicinal properties but also because they are affordable, environmentally friendly, and generally cause fewer side effects. Typically, herbal ointments are made by blending plant extracts with an appropriate base that facilitates the gradual release and effective absorption of active plant compounds. Bioactive substances like flavonoids, alkaloids, tannins, and terpenoids offer antimicrobial, anti-inflammatory, antioxidant, and wound-healing properties, making these products a promising alternative to synthetic topical medications. Among the many medicinal plants, Neem (Azadirachta indica) and Turmeric (Curcuma longa) are especially renowned for their skin-related benefits. Herbal ointments generally consist of a thick, semi-solid base infused with parts of medicinal plants such as seeds, leaves, roots, or flowers for external use on the skin. The key bioactive compound in turmeric, curcumin, is backed by scientific evidence for its wide range of health benefits, including improving cardiovascular health, and offering protective effects against Alzheimer’s disease and cancer. Curcumin is also known for its strong anti-inflammatory and antioxidant actions and may help relieve symptoms of arthritis and depression.1 2
Abdul Kalam Abdul Jabbar Nadaf, Anil Panchal*, Vishal Madankar, MD Tanvir Hamid Karajagikar, Formulation and Evaluation of Herbal Ointment from Neem and Turmeric Extract, Int. J. Sci. R. Tech., 2025, 2 (6), 221-232. https://doi.org/10.5281/zenodo.15589916
10.5281/zenodo.15589916
