Arihant college of pharmacy, kedgaon, Ahilyanagar.
Dissociative Identity Disorder (DID), previously known as Multiple Personality Disorder, is a complex and often misunderstood psychological condition characterized by the presence of two or more distinct identity states within an individual. These identities, or "alters," may differ in their behaviors, memories, and perceptions, often functioning autonomously from one another. DID is strongly associated with severe and prolonged trauma, typically occurring during early childhood, leading to disruptions in the development of a cohesive sense of self. Despite its inclusion in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), DID remains a subject of considerable debate due to its controversial etiology, diagnostic complexity, and the influence of sociocultural factors. Recent advancements in neuroimaging and psychometric tools have provided insights into the biological and psychological underpinnings of the disorder, demonstrating alterations in brain regions linked to memory, emotion regulation, and identity processing. Treatment approaches primarily involve psychotherapy aimed at trauma integration and identity unification, often supplemented by pharmacotherapy to manage comorbid conditions such as depression and anxiety. However, challenges persist, including misdiagnosis, stigmatization, and public misconceptions fueled by media portrayals. This review explores the historical evolution, clinical features, neurobiological findings, therapeutic strategies, and controversies surrounding DID. It highlights the need for further interdisciplinary research to refine diagnostic methods, improve treatment outcomes, and foster a more accurate understanding of this enigmatic disorder.
Dissociative Identity Disorder (DID), formerly referred to as Multiple Personality Disorder (MPD), is a chronic and complex psychological condition characterized by the presence of two or more distinct identity states, often referred to as “alters.” These identity states can differ significantly in terms of their behaviors, memories, preferences, and even physiological characteristics, such as handwriting styles or voice patterns. DID is considered the most severe form of dissociative disorders, a group of conditions that involve disruptions in memory, consciousness, identity, and perception. This disruption results in a fractured sense of self, making it difficult for individuals with DID to maintain a cohesive personal identity.
The origins of DID are strongly linked to trauma, particularly severe and repetitive abuse or neglect during early childhood. According to the trauma model, dissociation acts as a defense mechanism, allowing the child to psychologically escape overwhelming pain by compartmentalizing traumatic memories and emotions into separate identities. Over time, these compartmentalized states develop into distinct personalities, each serving specific functions, such as protecting the individual or managing particular emotions. This disorder is especially prevalent in individuals with histories of physical, emotional, or sexual abuse, often beginning before the age of six—a critical period for identity development.
Despite its recognition in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), DID remains a highly debated condition within the psychological and medical communities. Critics question the validity of DID as a distinct clinical entity, citing potential iatrogenic factors (symptoms induced by therapy), sociocultural influences, and misdiagnosis as contributing to its diagnosis. The sociocognitive model argues that DID symptoms may arise from suggestibility during therapy or from exposure to media portrayals of the disorder. On the other hand, proponents of the trauma model emphasize the consistency of DID presentations across different cultures and its association with well-documented traumatic histories.
The prevalence of DID is challenging to determine due to diagnostic complexities and frequent comorbidity with other mental health disorders. It is estimated that DID affects approximately 1-2% of the general population, though higher rates are reported in clinical settings. Common comorbidities include post-traumatic stress disorder (PTSD), depression, anxiety, substance use disorders, and borderline personality disorder. This overlap often complicates diagnosis, as symptoms such as memory gaps, emotional dysregulation, and identity disturbances may be attributed to other conditions.
Advances in neuroimaging and psychometric research have shed light on the neurobiological underpinnings of DID, offering tangible evidence to support its validity as a disorder. Studies have shown alterations in brain regions such as the hippocampus and amygdala, which are crucial for memory and emotional regulation. Functional MRI (fMRI) studies also reveal distinct neural activity patterns corresponding to different identity states, providing objective data that challenge the notion of DID as a purely sociocultural phenomenon. Treatment of DID focuses on addressing the underlying trauma and fostering integration or cooperation among the identity states. Psychotherapy remains the cornerstone of treatment, with approaches such as trauma-focused therapy, cognitive-behavioral therapy (CBT), and dialectical behavior therapy (DBT) commonly employed. Pharmacotherapy is typically used to manage comorbid conditions rather than treating DID directly. Emerging adjunctive therapies, including hypnosis and eye movement desensitization and reprocessing (EMDR), show promise but require further research to establish their efficacy. Despite ongoing advancements, DID continues to face significant stigma and public misunderstanding, largely fueled by sensationalized media portrayals. Popular films and books often depict DID in exaggerated or inaccurate ways, reinforcing stereotypes and detracting from the lived experiences of those affected by the disorder. This stigmatization poses barriers to diagnosis and treatment, underscoring the need for greater awareness and education among clinicians, researchers, and the general public. In conclusion, Dissociative Identity Disorder is a multifaceted and often misunderstood condition that demands a nuanced approach to diagnosis, treatment, and societal understanding. As research continues to unravel the complexities of DID, it is crucial to bridge the gaps between clinical practice, scientific investigation, and public perception to improve outcomes for those living with this challenging disorder.
ETIOLOGY:
The etiology of Dissociative Identity Disorder (DID) is complex and multifactorial, involving psychological, biological, and sociocultural components. Understanding the causes of DID requires examining the interplay of these factors, with a particular emphasis on the role of trauma, neurobiological changes, and social influences. Below is a detailed exploration of the primary etiological theories and contributing factors:
1. Trauma Model of DID
The trauma model is the most widely accepted explanation for DID. It posits that the disorder arises as an extreme response to severe and chronic trauma, especially during early childhood, when an individual's sense of self is still developing. Key aspects include:
1.1 Early Life Trauma
1.2 Dissociation as a Coping Mechanism
2. Neurobiological Factors
Emerging research highlights the biological underpinnings of DID, suggesting that neurobiological changes contribute to the development and maintenance of the disorder.
2.1 Brain Structures and Functions
2.2 Stress Response System
2.3 Neuroimaging Evidence
3. Sociocognitive Model
The sociocognitive model offers an alternative perspective, emphasizing the influence of social and cultural factors on the development of DID. While it does not deny the role of trauma, it highlights the following elements:
3.1 Social Influences
3.2 Therapeutic Suggestion
4. Genetic and Epigenetic Factors
While research into the genetic basis of DID is limited, some evidence suggests a hereditary component to dissociative tendencies.
4.1 Genetic Predisposition
4.2 Epigenetic Changes
5. Developmental and Personality Factors
Individual differences in temperament and early experiences play a significant role in determining susceptibility to DID.
5.1 Temperament
5.2 Cognitive Development
6. Interaction of Factors
The etiology of DID cannot be attributed to any single factor but rather involves a dynamic interplay of trauma, biological predispositions, and environmental influences. For instance:
Clinical Features and Diagnosis:
Clinical Features
1. Presence of Distinct Identity States (Alters)
2. Gaps in Memory (Amnesia)
3. Loss of Sense of Self
4. Emotional Dysregulation
5. Comorbid Conditions
6. Physical Manifestations
Diagnosis:
Diagnosis of DID
Diagnosing DID is challenging due to its overlapping symptoms with other psychiatric conditions and the stigma surrounding the disorder. Accurate diagnosis requires a comprehensive assessment by trained mental health professionals.
1. Diagnostic Criteria (DSM-5)
The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) provides the following criteria for DID:
2. Structured Diagnostic Tools
3. Clinical Observation
4. Differential Diagnosis
DID shares symptoms with several other conditions, necessitating careful evaluation to rule out:
5. Challenges in Diagnosis
Treatment:
1. Psychotherapy
Psychotherapy is the cornerstone of DID treatment. It aims to address dissociation, reduce symptoms, and integrate or harmonize identity states. Common therapeutic approaches include:
1.1 Phase-Oriented Treatment
Phase-oriented therapy is a widely accepted framework for treating DID, consisting of three main stages:
1.2 Cognitive-Behavioral Therapy (CBT)
CBT can help individuals identify and challenge distorted thought patterns that perpetuate dissociation. Techniques focus on managing triggers, improving emotional regulation, and fostering adaptive coping mechanisms.
1.3 Dialectical Behavior Therapy (DBT)
DBT is particularly effective for managing emotional dysregulation, self-harm, and interpersonal difficulties commonly seen in DID. Core components include mindfulness, distress tolerance, emotion regulation, and interpersonal effectiveness.
1.4 Trauma-Focused Therapy
Trauma-focused therapies aim to process and integrate traumatic memories. These approaches include:
1.5 Hypnotherapy
Hypnosis may be used as an adjunct to psychotherapy, helping individuals access dissociated memories and fostering communication between alters. However, it must be applied cautiously to avoid the risk of suggestion or retraumatization.
2. Pharmacotherapy
There is no specific medication for DID itself, but pharmacotherapy is often used to manage comorbid conditions and alleviate specific symptoms.
2.1 Medications for Comorbid Disorders
2.2 Limitations
3. Adjunct Therapies
In addition to psychotherapy and medication, several adjunctive approaches can support the treatment process:
3.1 Eye Movement Desensitization and Reprocessing (EMDR)
3.2 Mindfulness and Meditation
3.3 Creative Therapies
4. Building Cooperation Among Alters
While not all individuals with DID aim for full integration, fostering cooperation and communication between alters is a critical therapeutic goal. Techniques include:
5. Psychoeducation and Support
Education about DID is essential for both individuals and their families:
6. Challenges in Treatment
7. Emerging Approaches and Future Directions
Case study:
A case of a 55-year-old Caucasian female with a history of substance use disorder and a comorbid bipolar disorder, who presented to the local general hospital with a history of the fragmentation of a single personality into different personalities under emotional stress and under the influence of a drug. Multiple aspects of her personalities were reported, including the following: a personality of a seven-year-old child, a personality that would behave as a teenager, and another that acted like a male person in addition to her normal 55-year-old personality. She reported that she had been constantly dominated by her alternate personalities and became aware of their existence when people around her informed her, usually after a situation ended. She reported that stressful situations and substance abuse could aggravate the fragmentation of her personality. This was found to be mostly an involuntary phenomenon with seldom memory of the event.
While transitioning between these personalities, she was found to be violent even to people who were close to her. This could range from being suicidal to homicidal for which she was arrested twice in the past. She had to be isolated and restrained by being locked in a room and calling the police. As a result, she was hospitalized in a mental institution for a significant period at least two to three times in the past. Under the influence of stress or substances like marijuana or cocaine, her personality would split into various personalities. These states were very different from one another in terms of age or gender.
One of her alternate personalities behaved as a seven-year-old child and would show the same interests and choices that included becoming moody or a self-arrogant personality. While in these states, she could hurt herself or had weeping spells if her wants were not met.
Another personality acted as a teenager with some sharp choices and dressing. Increase in substance abuse, alcohol use, and smoking would lead to multiple cases of fights or homicidal attacks, with some incidents of self-harming events. Multiple scars were found on the dorsal side of her right hand. Her speech was found to be pressured and she would repeat the same words/ conversations.
The next personality was diagnosed to be a temporary transition to the opposite gender (a male). There was a change in voice and behavior. This included male dressing, language, a perception of male body parts, choices of friends, and attraction towards females, including sexual behavior.
The normal state of a 55-year aged female was the default personality that made her feel most comfortable. She reported that she had anxiety during a personality state transition, as it could occur at any time, and involuntarily, but mostly in stressful situations and during substance abuse. More violent and harmful events were reported when someone tried to meet the patient alone rather than in a group.
The treatment included psychotherapy with cognitive behavioral therapy addressing stress and substance use disorder. The psychotherapeutic treatment lasted for at least six months. The dual treatment of drug therapy was also involved to calm her down. The patient was prescribed escitalopram to reduce her anxiety symptoms. She believed that the anxiety pills were really helpful. After six months, the patient's condition was not drastically different. However, she believed her stress was getting better. The patient was further followed up for the next one year and the treatment continues to date.
Controversies and Criticisms:
1. Validity of DID as a Diagnosis
1.1 Skepticism Among Mental Health Professionals
1.2 Sociocognitive Model of DID
The sociocognitive model suggests that DID is not a naturally occurring disorder but a condition shaped by sociocultural influences and therapeutic suggestion.
2. Controversies in Etiology
2.1 Trauma Model vs. Sociocognitive Model
The trauma model and sociocognitive model offer competing explanations for DID’s origins:
2.2 Lack of Objective Evidence for Trauma
2.3 False Memory Syndrome
3. Diagnostic Challenges
3.1 Overdiagnosis vs. Underdiagnosis
3.2 Reliability of Diagnostic Tools
4. Prevalence Controversies
4.1 Varying Prevalence Rates
4.2 Cultural Influence
5. Media and Public Misrepresentation
5.1 Sensationalized Portrayals
5.2 Impact on Public Perception
6. Treatment-Related Controversies
6.1 Risk of Iatrogenesis
6.2 Lack of Standardized Treatment Protocols
6.3 Prolonged and Costly Therapy
7. Legal and Ethical Issues
7.1 DID in Legal Contexts
7.2 Ethical Concerns in Therapy
8. Efforts to Address Controversies
8.1 Research Advancements
8.2 Education and Awareness
8.3 Development of Standardized Guidelines
CONCLUSION
Dissociative Identity Disorder (DID) remains a highly debated and complex psychiatric condition, with its origins, diagnosis, and treatment frequently scrutinized. While the trauma model provides a compelling explanation linking DID to early-life adversity, alternative views, such as the sociocognitive model, challenge its validity, citing cultural, therapeutic, and media influences. The lack of universally accepted diagnostic criteria and standardized treatment protocols further complicates the disorder's clinical landscape.
Despite controversies, significant progress has been made in understanding the neurobiological and psychological underpinnings of DID, validating it as a legitimate mental health condition for many. However, sensationalized media portrayals and therapeutic missteps continue to perpetuate stigma and skepticism. Bridging these divides requires a balanced approach, integrating rigorous research, ethical therapeutic practices, and increased education for both clinicians and the public. By fostering a more evidence-based and empathetic perspective, the mental health community can better support individuals living with DID, ensuring their unique needs are met with compassion and care.
REFERENCE
Sudarshan Kalagate, Madhura Jadhav, Jitesh Batra, Multiple Personality Disorder (Dissociative Identity Disorder), Int. J. Sci. R. Tech., 2024, 1 (11), 230-239. https://doi.org/10.5281/zenodo.14235007
10.5281/zenodo.14235007