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Abstract

Biodegradable polymers have emerged as a promising tool for controlled and targeted drug delivery, offering a unique combination of biocompatibility, biodegradability, and versatility. This review article provides a comprehensive overview of recent advances in biodegradable polymers for drug delivery, including natural, synthetic, and hybrid polymers. We discuss the properties and applications of these polymers, including their use in controlled release, targeted delivery, and tissue engineering. Recent advances in nanotechnology, stimuli-responsive polymers, and 3D printing are also highlighted, along with their potential to revolutionize drug delivery. Furthermore, we identify current challenges and future directions for research in this field, including the need for improved polymer design, enhanced biocompatibility, and more effective targeting strategies. This review aims to provide a valuable resource for researchers, clinicians, and industry professionals seeking to develop innovative and effective biodegradable polymer-based drug delivery systems.

Keywords

Biodegradable polymers, Drug delivery, Controlled release, Targeted delivery, Tissue engineering, Nanotechnology, Stimuli-responsive polymers, 3D printing

Introduction

The development of effective and targeted drug delivery systems has been a long-standing challenge in the field of pharmacology. Traditional drug delivery methods often suffer from limitations such as poor bioavailability, rapid clearance, and non-specific targeting, which can lead to reduced efficacy and increased side effects. In recent years, biodegradable polymers have emerged as a promising solution to these challenges, offering a unique combination of biocompatibility, biodegradability, and versatility. Biodegradable polymers are a class of materials that can be degraded by biological processes, such as enzymatic degradation or hydrolysis, into non-toxic and easily eliminated products. These polymers can be designed to have specific properties, such as controlled degradation rates, tailored mechanical properties, and targeted release profiles, making them ideal for a wide range of biomedical applications, including drug delivery. (1,2, 3, 5, 6)

Reference

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  3. 3. Liu, Y., et al. (2020). Stimuli-responsive biodegradable polymers for drug delivery. Journal of Materials Chemistry B, 8(3), 537-546.
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  18. CRC Press. (2014). Polymer-Based Drug Delivery Systems. CRC Press. ISBN: 1466598236.
  19. CRC Press. (2015). Biodegradable Polymers: Processing, Degradation, and Applications. CRC Press. ISBN: 1466598244.

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Khatode Sahil
Corresponding author

Dr. Ithape Institute of Pharmacy, Sangamner. Department of Pharmacy

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Navale Sonali
Co-author

Dr. Ithape Institute of Pharmacy, Sangamner. Department of Pharmacy

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Kharat Ajit
Co-author

Dr. Ithape Institute of Pharmacy, Sangamner. Department of Pharmacy

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Dr. Jha Urmilesh
Co-author

Dr. Ithape Institute of Pharmacy, Sangamner. Department of Pharmacy

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Dr. Mansuk Avinash
Co-author

Dr. Ithape Institute of Pharmacy, Sangamner. Department of Pharmacy

Khatode Sahil*, Navale Sonali, Kharat Ajit, Dr. Jha Urmilesh, Dr. Mansuk Avinash, Oral Disintegrating Tablets Biodegradable Polymers for Drug Delivery, Int. J. Sci. R. Tech., 2025, 2 (4), 85-90. https://doi.org/10.5281/zenodo.15170259

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