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  • Formulation and Evaluation of Herbal Foot Crack Cream from Aegle Marmelos Leaf Extract

  • 1Assistant Professor Department of Pharmaceutics Delight college of pharmacy Koregaon Bhima, Pune, Maharashtra, India-412216. 
    2Research Scholar, Department of Pharmaceutics, Delight College of Pharmacy, Koregaon Bhima, Pune, Maharashtra. India-412216
     

Abstract

The primary objective of this study is to develop and assess an herbal foot crack cream. The herbal foot crack cream was formulated by oil-in-water (O/W) cream base conventional emulsification technique by using ethanolic extract of Aegle marmelos leaf extract. The formulated cream was also evaluated for their physical and chemical properties including pH, spreadability, washability, stability, viscosity, skin irritancy. The pH of herbal foot crack cream was found to be 6.5 which is acceptable in skin irritancy test. This research aims to highlight the therapeutic benefits of Aegle marmelos. Crack heel is a prevalent skin condition character by dryness, thick skin, and painful splits due to environmental factors, lack of hydration, or microbial infections. These findings suggest that Aegle marmelos based cream may serve as a potential herbal formulation for the treatment of wound healing and related skin condition.

Keywords

Aegle marmelos, Antibacterial, foot cracks, skin care, wound healing Leaf Extract

Introduction

The skin is the body's largest organ, covering approximately 20 square feet. It consists of three layers. The outermost layer, called the epidermis, acts as a waterproof shield and determines our skin tone. Cosmetics are widely used products designed to enhance and maintain the appearance of the face and other body parts such as the skin, eyes, hair, and hands. Herbal cosmetics are a special category that combines cosmetic use with active biological ingredients, nutraceuticals, and pharmaceutical properties. Cosmetics are primarily used for cleansing and beautifying the skin. Their use dates to ancient Egypt around 4000 B.C. On the other hand, pharmaceuticals are drug-based products used to prevent, treat, or cure diseases and influence the body's structure or function. The skin on the feet is especially prone to dryness, roughness, and cracking. Conditions such as athlete’s foot, eczema, psoriasis, thyroid issues, and diabetes are common causes of cracked heels. Keeping the skin healthy is vital for overall well-being. Natural treatments are often considered affordable and safe alternatives.1

This review highlights various plants used in the treatment of skin diseases, summarizing the significant scientific developments made in this field over the past 17 years. These plants also serve as valuable raw materials for the development of new synthetic compounds. Herbs used in cosmetic formulations possess a range of beneficial properties, including antioxidant, anti-inflammatory, antiseptic, and antibacterial effects.

Reference

  1. Bhavana SN, Nazim M, Reshma N, Formulation and Evaluation of Herbal Foot crack Cream, International Journal of Pharmaceutical Research and Application, 2024; 9, 5; 08-12. DOI: 10.35629/4494-09050812
  2. Karande S, Gilbile P, Bhogan S, Shinde M, Lad T, Patil P, Patel A, FORMULATION AND EVALUTION OF HERBAL HEEL CRACK CREAM, Word Journal of Pharmacy and Pharmaceutical Science, 2024; 13, 7,623-642. DOI:10.20959/wjpps20247-27448
  3. Mujeeb F, Bajpai P, Pathak N, Phytochemical evaluation, antimicrobial activity, and determination of bioactive components from leaves of Aegle marmelos, Biomed Res Int, 2014; 497606. DOI: 10.1155/2014/497606
  4. Cibin TR, Devi DG, Abraham A, Chemoprevention of skin cancer by the flavonoid fraction of Saraca asoka Phytother Res, 24: 666-672. https://doi.org/10.1002/ptr.29505
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  6. Patkar AN, Desai NV, Ranage A, A Review on Aegle Marmelos: A Potential Medicinal Tree, International Research Journal of Pharmacy IRJP 2012, 3(8), 86-91.
  7. Kumar, S., Kumar, V., & Prakash, O. (2011). Aegle marmelos (L.) Correa: A potential source of phytomedicine. Journal of Medicinal Plants Research, 5(9), 1497-1507. DOI: 10.5897/JMPR.9000056
  8. Patil MR, Wagh PN Aegle marmelos: A versatile medicinal plant, Journal of Pharmacognosy and Phytochemistry, 2012; 1(2), 25–29. DOI: 10.4103/0975-241X.114852
  9. Sabu MC, Kuttan R, Antidiabetic activity of Aegle marmelos and its relationship with its antioxidant properties, Indian Journal of Physiology and Pharmacology, 2004; 48(1), 81–88. DOI: 10.1016/j.jep.2003.11.025
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Anil Panchal
Corresponding author

Assistant professor, Department of Pharmaceutics ,Delight College of Pharmacy, Koregaon Bhima, Pune. Maharashtra, India-412216.

Photo
MD. Tanvir Hamid Karajagikar
Co-author

Research Scholar, Department of Pharmaceutics, Delight College of Pharmacy, Koregaon Bhima, Pune, Maharashtra. India-412216.

Anil Panchal, MD. Tanvir Hamid Karajagikar, Formulation and Evaluation of Herbal Foot Crack Cream from Aegle Marmelos Leaf Extract, Int. J. Sci. R. Tech., 2025, 2 (6), 539-548. https://doi.org/10.5281/zenodo.15676083

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