1Research Scholar, Department of Pharmacognosy, Late Narayandas Bhawandas Chhabada Institute of Pharmacy, Raigaon, Satara. Dist: Satara, Maharashtra. 415020
2Assistant Professor, Department of Pharmacology, Late Narayandas Bhawandas Chhabada Institute of Pharmacy, Raigaon, Satara. Dist: Satara, Maharashtra. 415020
This study employs the wet granulation method to develop and evaluate a multi-nutrition, herbal tablet consisting of Tulsi, Cinnamon, Clove and Ginger. The objective is to assess the tablet's quality through various factors, including thickness, hardness, weight variation, and friability. These potent herbs are incorporated due to their nutritional and therapeutic properties. The ingredients are effectively transformed into a tablet form for easy consumption using the wet granulation technique. Analyzing the tablet's physical properties provides valuable insights into its effectiveness and user acceptance. The findings of this research could offer benefits for dietary supplementation and health by improving our understanding of the formulation and quality assessment of multi-nutrient herbal tablets.
Nutrition, the study of food and its impact on health, is essential for disease prevention and overall well-being. The significance of a healthy diet in maintaining good health has been acknowledged since ancient times. In modern society, with the increase in chronic diseases and lifestyle-related health issues, the need for a balanced diet rich in vital nutrients is more evident than ever.The use of herbal supplements for health promotion and dietary support has gained popularity due to their believed therapeutic effects and minimal side effects.Herbs like amla (Indian gooseberry), tulsi (holy basil), cinnamon, licorice, mint, and ginger are highly valued for their nutritional and healing properties. These plants have been revered across various cultures for their health benefits, such as immune-boosting, digestive aid, and antioxidant effects. Research into the formulation and evaluation of herbal products, particularly tablets for easy consumption, has significantly increased due to the growing demand for natural remedies1. Combining multiple herbal ingredients into a single multi-nutrient tablet offers a promising approach to enhance overall health and well-being. This study aims to examine the preparation and evaluation of a multi-nutrient herbal tablet containing ginger, mint, amla, tulsi, cinnamon, and licorice. These botanicals are transformed into a unified tablet using the effective wet granulation method, ensuring consistency and potency in the final product. The study focuses on evaluating key factors that influence the tablet's effectiveness and quality, such as weight variation, hardness, thickness, and friability, which are crucial for its stability, efficacy, and consumer acceptance. This research contributes to the growing field of herbal medicine and nutraceuticals by exploring the formulation process and establishing quality standards for the tablet. The findings suggest potential for developing multi-nutrient herbal supplements that provide a natural, holistic approach to maintaining health and preventing disease. The concept of using food for health benefits beyond basic nutrition is gaining traction in both public and scientific circles2. Nutraceuticals—natural compounds extracted or purified from food—are believed to offer physiological benefits and prevent chronic diseases. The term was coined by
Dr. Stephen L. De Felice, founder of the Foundation for Innovation in Medicine. Nutraceuticals, often referred to as "functional foods," have sparked debate due to their blurred lines between food and medicine3.
With growing public demand and favorable demographic and socioeconomic trends, research indicates that nearly two-thirds of the world’s population uses plant-based remedies for reasons such as accessibility, safety, cost, and cultural tradition. The health benefits of food have been studied for thousands of years.
The reasons for shift towards nutraceuticals are:
Herbs used in our research:
Taxonomy & Classification
Kingdom: Plantae (Plants)
Phylum: Angiosperms (Flowering Plants)
Class: Eudicots
Order: Lamiales
Family: Lamiaceae (Mint family)
Genus: Ocimum
Species: Ocimum tenuiflorum5.
Benefits of The Herb
Taxonomy & Classification
Kingdom: Plantae
Clade: Angiosperms
Order: Laurales
Family: Lauraceae
Genus: Cinnamomum
Common Species:
Benefits of The Herb
Taxonomy & Classification
Kingdom: Plantae
Clade: Angiosperms
Order: Zingiberales
Family: Zingiberaceae
Genus: Zingiber
Species: Zingiber officinale
Common Names:
Benefits of The Herb
Taxonomy & Classification
Kingdom: Plantae (Plants)
Phylum: Angiosperms (Flowering Plants)
Class: Eudicots Order: Myrtale Family: Myrtaceae Genus: Syzygium
Species: Syzygium aromaticum11.
Benefits of The Herb
Procedure for formulation of herbal tablet
|
Ingredient |
Quantity (mg per tablet) |
Total Quantity (mg for 20 tablets) |
|
Tulsi (Holy Basil) Powder |
150 mg |
3 g |
|
Cinnamon Powder |
100 mg |
2 g |
|
Ginger Powder |
100 mg |
2 g |
|
Clove Powder |
50 mg |
1 g |
|
Binder (e.g., Microcrystalline Cellulose) |
25mg |
0.5 g |
|
Filler (e.g., Lactose or Starch) |
50 mg |
1 g |
|
Anti-caking agent (e.g., Magnesium Stearate) |
25 mg |
0.5 g |
Manufacturing Process:
RESULTS AND DISCUSSION
Tablets were prepared containing the crude drugs like clove, cinnamon, ginger, tulsi, etc.
Evaluation Test for Multi-Nutrition Tablet
|
Sr. No. |
Test |
Procedure |
Observation |
|
1 |
Organoleptic Test |
Observe the colour, Odor, texture, and taste of the tablet. |
Colour: Brownish with a slight greenish hue from Tulsi and reddish tint from Cinnamon. |
|
Odor: Spicy, herbal, with a warm fragrance from Clove and Cinnamon. |
|||
|
Texture: Smooth surface, firm with a slight crumbly texture. |
|||
|
Taste: Spicy, herbal, with a mild bitterness. |
|||
|
2 |
Weight Uniformity Test |
Weigh tablets 1, 2, and 3. |
Tablet 1: 500 mg, Tablet 2: 505 mg, Tablet 3: 497 mg. |
|
Compare the weight variation to ensure it falls within the specified limit. |
Weight variation within ±5% of the target weight (500 mg). |
||
|
3 |
Disintegration Time |
Place tablets in a disintegration apparatus and record the time taken for them to disintegrate. |
Tablet 1: 6 minutes, Tablet 2: 5.5 minutes, Tablet 3: 6.2 minutes. |
|
Ensure that the disintegration time meets the specified limit. |
Disintegration time is under 15 minutes (Ideal: 6-8 minutes). |
||
|
4 |
Hardness Test |
Use a hardness tester to measure the force required to break the tablet. |
Tablet 1: 6 kg, Tablet 2: 5.8 kg, Tablet 3: 6.2 kg. |
|
Ensure the tablet hardness is within the acceptable range for handling. |
Hardness between 4-8 kg, suitable for handling without crumbling. |
||
|
5 |
Friability Test |
Tablets are subjected to a friability test by rotating them in a drum to simulate handling and transportation. |
Tablet 1: 0.4%, Tablet 2: 0.5%, Tablet 3: 0.3%. |
|
Measure the percentage weight loss to determine friability. |
Friability under 1%, no significant breakage or damage. |
||
|
6 |
Dissolution Test |
Tablets are placed in a dissolution apparatus with a specified medium and tested at 30-minute intervals. |
Tablet 1: 85% dissolved at 30 minutes, Tablet 2: 80% dissolved, Tablet 3: 90% dissolved. |
|
Measure the percentage of drug released in the dissolution medium over the specified time period. |
≥75% dissolved in 30 minutes, ensuring effective release of active ingredients. |
CONCLUSION
The formulation of a multi-nutrition herbal tablet using Tulsi, cinnamon, ginger, and clove was successfully developed and evaluated using basic and advanced tests. The results indicate that the tablets meet key quality parameters, including uniformity in weight, proper hardness, friability, and acceptable disintegration time. The herbal ingredients contribute beneficial bioactive compounds, ensuring potential health benefits such as antioxidant, anti-inflammatory, and immune-boosting properties
REFERENCE
Sanskar Biradar*, Tushar Gaikwad, Formulation and Evaluation of Multi Nutrition Herbal Tablet, Int. J. Sci. R. Tech., 2025, 2 (4), 244-249. https://doi.org/10.5281/zenodo.15199306
10.5281/zenodo.15199306
