View Article

  • Formulation and Evalution of Multinutrient Herbal Tablet

  • 1Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216
    2Assistant Professor, Department of Pharmacology, Delight College of Pharmacy, Koregaon Bhima, Pune, Maharashtra, India-412216
     

Abstract

This study employs the wet granulation method to develop and evaluate a multi- nutrient herbal tablet consisting of Tulsi, cinnamon, clove and ginger. The objective is to assess the tablet's quality through various factors, including thickness, hardness, weight variation, and friability. These potent herbs are incorporated due to their nutritional and therapeutic properties. The ingredients are effectively transformed into a tablet form for easy consumption using the wet granulation technique. Analyzing the tablet's physical properties provides valuable insights into its effectiveness and user acceptance. The findings of this research could offer benefits for dietary supplementation and health by improving our understanding of the formulation and quality assessment of multi-nutrient herbal tablets.

Keywords

Multi-nutrient herbal tablet Tulsi, Cinnamon, Clove, Ginger, Thickness, Hardness, Weight variation, Friability, Wet granulation

Introduction

Nutrition—the science of how food influences health—plays a vital role in preventing illness and supporting overall wellness. The importance of a nutritious diet has been recognized since ancient times, but in today’s world, where chronic diseases and lifestyle-related conditions are on the rise, the need for a nutrient-rich, balanced diet is more critical than ever. Herbal supplements have become increasingly popular due to their perceived health benefits and low risk of side effects. Medicinal plants such as amla (Indian gooseberry), tulsi (holy basil), cinnamon, licorice, mint, and ginger are widely appreciated for their nutritional and therapeutic properties. These herbs have long been used across cultures to support the immune system, improve digestion, and act as antioxidants. As interest in natural health solutions grows, there has been a surge in research focused on developing herbal formulations, especially tablets that offer convenient consumption. Combining several herbs into one multi-nutrient tablet presents a promising strategy for enhancing health and well-being. This study explores the formulation and assessment of a herbal tablet composed of ginger, mint, amla, tulsi, cinnamon, and licorice. Using the wet granulation method ensures uniformity, potency, and quality in the final product. Key physical characteristics such as weight variation, hardness, thickness, and friability are evaluated to determine the tablet’s stability, effectiveness, and consumer appeal. This research supports the advancement of herbal medicine and nutraceuticals by highlighting the formulation process and defining quality benchmarks. The concept of using food to achieve health benefits beyond basic nutrition—known as nutraceuticals—is gaining recognition among both the public and scientific communities. Coined by Dr. Stephen L. De Felice, founder of the Foundation for Innovation in Medicine, the term refers to bioactive compounds derived from food that offer potential health benefits or disease prevention. Often called "functional foods," nutraceuticals occupy a space between food and medicine, sparking ongoing discussion. Current trends suggest that nearly two-thirds of the global population turns to plant-based remedies due to their affordability, safety, accessibility, and alignment with cultural practices. Historically, the health value of food has been studied for millennia. Several factors are driving the shift toward nutraceuticals:

  1. Rising concerns over the increasing cost of healthcare.
  2. Disappointment in the effectiveness of conventional pharmaceutical treatments.
  3. Awareness that modern, chemically treated, and genetically modified food lacks essential nutrients.
  4. A growing preference for preventive care over treatment.
  5. Individuals with chronic conditions who have not found relief through standard medical approaches.
  6. Economic challenges that make alternative treatments more appealing.

Drug Profile:

  1. Tulsi (Osmium sanctum)

Reference

  1. Cenci A and Chingwaru W. The role of functional food nutraceutical and food supplements in intestinal health. Nutrients. 2010.
  2. Chauhan B, Kumar G, Kalam N and Ansari SH. Current concepts and prospects of herbal nutraceutical: A review Adv Pharm Technol Res. 2013.
  3. Shah VP. In vitro dissolution profile comparison statistics and analysis of the similarity factor. Pharm Res 1998.
  4. Srinath KR, Chowdary P, Palanisamy P, Vamsi K et al, “Formulation and Evaluation of Effervescent tablets of Paracetamol”, International Journal of Pharmaceutical Research & Development, 2011.
  5. Tamilvanan S and Biswanath SA. In Vitro and In Vivo evaluation of single-unit commercial conventional tablet and sustained-release capsules compared with multiple unit polystyrene microparticles dosage forms of ibuprofen. AAPS Pharm Sci Tech 2006.
  6. Thakur S and Brisha B; Shouvik KN. Formulation and Characterization of Herbal Tablets for the Management of Tablet. EPRA (IJRD), 2021.
  7. Deng R. A review of the hypoglycemic effects of five commonly used herbal food supplements. Recent Pat Food Nutra Agric. 2012.
  8. Aslani A and Fattahi F. Formulation, Characterization and Physicochemical Evaluation of Potassium Citrate Effervescent Tablets. Advanced Pharmaceutical Bulletin, 2013.
  9. Athawale RB, Rege SS and Tawanda V. Formulation and evaluation of herbal nutraceutical tablet for malnutrition. Int J Ayurvedic Herbal 2011.
  10. Hussain AI, Anwar F, Nigam PS, Ashraf M, Gilani AH. Seasonal variation in content, chemical composition and antimicrobial and cytotoxic activities of essential oils from four Mentha species. J Sci. Food. Agric. 2010.
  11. Lachman L, Lieberman HA and Konig Lathe theory and practice of industrial pharmacy.3rdedition Varghese publishing house.2009.
  12. Indian Pharmacopoeia: Ministry of Health and Family Welfare, Government of India. Published by the Indian Pharmacopoeia commission: Ghaziabad; 2010.
  13. Pandey MM, Rastogi S and Rawat AKS. Indian traditional Ayurvedic system of medicine and supplementation. Evid Based Complement Alternat Med. 2013.
  14. Aslani A and Fattahi F. Formulation, Characterization and Physicochemical Evaluation of Potassium Citrate Effervescent Tablets. Advanced Pharmaceutical Bulletin, 2013.
  15. Athawale RB, Rege SS and Tawanda V. Formulation and evaluation of herbal nutraceutical tablet for malnutrition. Int J Ayurvedic Herbal 2011.
  16. Hussain AI, Anwar F, Nigam PS, Ashraf M, Gilani AH. Seasonal variation in content, chemical composition and antimicrobial and cytotoxic activities of essential oils from four Mentha species. J Sci. Food. Agric. 2010.
  17. Lachman L, Lieberman HA and Konig Lathe theory and practice of industrial pharmacy.3rdedition Varghese publishing house.2009.
  18. Indian Pharmacopoeia: Ministry of Health and Family Welfare, Government of India. Published by the Indian Pharmacopoeia commission: Ghaziabad; 2010.
  19. Pandey MM, Rastogi S and Rawat AKS. Indian traditional Ayurvedic system of medicine and supplementation. Evid Based Complement Alternat Med. 2013.

Photo
Dnyaneshwar Lande
Corresponding author

Research Scholar, Department of Pharmaceutics, Dr. Babasaheb Ambedkar Technological University, Pune, Maharashtra, India-412216

Photo
Mahadev Munde
Co-author

Assistant Professor, Department of Pharmacology, Delight College of Pharmacy, Koregaon Bhima, Pune, Maharashtra, India-412216

Dnyaneshwar Lande*, Mahadev Munde, Formulation and Evalution of Multinutrient Herbal Tablet, Int. J. Sci. R. Tech., 2025, 2 (6), 306-317. https://doi.org/10.5281/zenodo.15614363