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Abstract

The aim of this study was to develop and evaluate oral patches containing herbal extracts with antiulcer activity. Four herbal extracts (guava, lavender, thyme and chamomile) were selected based on their traditional use in gastric disorders. The results showed that the buccal patches showed significant anti-ulcer activity, with guava and lavender showing the highest activity. The patch showed faster drug release and better immune response compared to the control group. This study demonstrates the potential of herbs as a novel and effective treatment for oral ulcer.

Keywords

Herbal formulation, Buccal Patches, Ulcer, Anti-ulcer, Guava (Psidium guajava leaves), Lavender (Lavandula angustifolia), Thyme (Thymus vulgaris), Chamomile

Introduction

Ulcer:

Mouth ulcers, medically known as aphthous ulcers, are diseases of the mucous membranes of the oral cavity. Although they are common and often associated with many conditions, most conditions do not indicate a serious problem. However, persistent, and non-healing disease may be a sign of oral disease. These lesions may appear singly or in groups called "ulcers." Once they form, inflammation and/or secondary infection may cause the sore to become permanent.

Reference

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Shivraj Mane
Corresponding author

Progressive Education Society’s Modern College of Pharmacy, Nigdi, Pune, Maharashtra, India- 411044

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Anushka Kamble
Co-author

Progressive Education Society’s Modern College of Pharmacy, Nigdi, Pune, Maharashtra, India- 411044

Photo
Lochan Khadke
Co-author

Progressive Education Society’s Modern College of Pharmacy, Nigdi, Pune, Maharashtra, India- 411044

Photo
Shweta Mhetre
Co-author

Progressive Education Society’s Modern College of Pharmacy, Nigdi, Pune, Maharashtra, India- 411044

Shivraj Mane*, Anushka Kamble, Lochan Khadke, Shweta Mehtre, Herbal Formulation and Evaluation of Buccal Patches Showing Anti-Ulcer Activity, Int. J. Sci. R. Tech., 2025, 2 (3), 495-504. https://doi.org/10.5281/10.5281/zenodo.15090016

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