Delight College of Pharmacy, Koregaon Bhima, Pune, Maharashtra, India-412216
Diabetes mellitus is a long-term disease that happens when the pancreas does not make enough insulin, or when the body cannot use the insulin properly. More than 415 million people in the world have diabetes, and this number may reach 642 million by 2040. The World Health Organization (WHO) says that by 2030, diabetes will be the seventh leading cause of death. Most people with diabetes are treated with insulin injections or tablets, but these treatments are sometimes hard for patients to follow regularly. In recent years, scientists have started focusing on transdermal systems – special patches or devices that deliver medicine through the skin. These systems have many benefits compared to injections and tablets. Studies show that medicines given through the skin are better absorbed because they do not pass through the liver first. They also release the medicine slowly over time, which helps keep blood sugar levels steady and reduces the need to take medicine many times a day. This makes it easier for patients to follow their treatment and improves their overall health. In short, using skin patches for diabetes treatment is a new and promising method that can make diabetes control easier and more effective.
Diabetes mellitus is a long-term illness where the amount of sugar (glucose) in the blood becomes too high. This happens because the body does not make enough insulin. If diabetes is not treated, it can cause serious health problems like stroke, heart disease, or even death. Type 2 diabetes is more common than type 1. About 425 million people in the world have diabetes. According to the World Health Organization (WHO), diabetes cases have gone up to 4.7%, and it may become the seventh biggest cause of death in the world by 2030.Insulin is very important to control diabetes. In type 1 diabetes, the body’s cells that make insulin (called beta cells) are destroyed, so no insulin is made. In type 1A diabetes, this happens because the immune system attacks these cells. Type 1B (idiopathic diabetes) happens when beta cells are lost, but the cause is unknown. Type 2 diabetes is usually linked to family history, lifestyle, and environment. Gestational diabetes happens during pregnancy when the body makes less insulin, which raises blood sugar levels1.Type 1 diabetes (T1DM) happens when the beta cells in the pancreas (found in the islets of Langerhans) are destroyed. These cells make insulin, so their loss causes a complete lack of insulin in the body. Type 1A diabetes, also called insulin-dependent diabetes, is caused by the immune system attacking and destroying the beta cells. The speed of destruction can be different for different people. Type 1B diabetes, or idiopathic diabetes, is when beta cells are lost but there is no clear immune system attack or other known reason for insulin deficiency2.
Amin Shaikh*, Pratiksha Ravankole, Priyanka Konde, Fiza Mulani, Transdermal Drug Delivery Systems in Diabetes Management: A Review, Int. J. Sci. R. Tech., 2025, 2 (9), 247-253. https://doi.org/10.5281/zenodo.17197138
10.5281/zenodo.17197138
