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S.N.D. College of Pharmacy, Babhulgaon (Yeola), India (423401)
Wound healing is a multifaceted biological process involving hemostasis, inflammation, proliferation, and tissue remodeling. The inflammatory phase, while essential for pathogen clearance and tissue repair, must be precisely regulated to prevent chronic inflammation and impaired healing. Medicinal herbs have long been used in traditional medicine for their wound-healing and anti-inflammatory properties. Many contain bioactive compounds such as flavonoids, alkaloids, saponins, and terpenoids that modulate key molecular pathways involved in inflammation and tissue regeneration. Notable herbs such as Centella asiatica, Curcuma longa (turmeric), Aloe vera, Calendula officinalis, and Chamomilla recutita have demonstrated efficacy in preclinical and clinical studies. Their mechanisms of action include inhibition of pro-inflammatory cytokines (e.g., TNF-?, IL-1?), enhancement of collagen synthesis, promotion of angiogenesis, and antioxidant activity. This review summarizes current findings on the phytochemistry, pharmacological actions, and therapeutic potential of selected anti-inflammatory herbs in wound healing. Diseases can be treated with medicinal herbs. Numerous illnesses, including rheumatoid arthritis, immune-mediated disorders, diabetes, heart attacks and more, can be classified as inflammatory. Among the plants discussed in this review are fenugreek, chamomile, ginger, ashwagandha, and turmeric. Since herbal medicine and lifestyle changes are used to alleviate inflammation, it is not a one-dimensional solution. Since the treatment of inflammation is not a single configuration relief, in this review article we tried to introduce to approach multidimensional medicinal access to treat inflammation, with the help of anti-inflammatory plants and by Modification our life style by exercise and diet. Vascular tissues intricate biological reaction to damaging stimuli like infections, damaged cells, or irritants includes inflammation. Redness, swollen joints, joint pain, stiffness and loss of joint function are some of its symptoms. The chemical diversity of natural goods makes them a great source for the development of new medications. The pharmaceutical management of inflammation by substances that vitally balance the inflammatory cascade is the primary topic of this review. Nevertheless, there isn?t a single agent that is specifically involved in wound healing that is sold in the healthcare industry. We will examine many agents or factors influencing inflammation in wound healing in this review.
Inflammation: Inflammation is a normal, protective response to tissue injury caused by physical trauma, noxious chemicals or microbiological agents1.Living tissue’s extreme reaction to any type of damage is inflammation. Pain, redness, heat or warmth, and swelling are the four main signs of inflammation. The arterioles in the surrounding tissue widen when any portion of the human body is injured. This results in increased blood flow to the region (redness)2. In order to repair tissue damage, wound healing involves a complex web of overlapping biological processes. Haemostasis, inflammation, tissue proliferation, and maturation are the main stages, and they involve a wide variety of cell types, some of which are local and others that are drawn in after an injury3.Herbal medicine is one of the most important medicines for treating all kinds of diseases. It is best therapy having least side effects and best Curative effects. In this review some plants which their anti-inflammatory effect has been thoroughly evaluated in many research articles and review articles which are of experimental based. Curcuma long, Zingiber officinale, Rosa Canina, cassia fistula, salvia officinale, Borago Officinale, Rosmarinus officinale, evening Primrose, Ribesnigrum, Oleaeuropea Herpagophytum, Elaeagnusangustifolia these are the plants which have strong anti-inflammatory activity and have been used for the of many inflammatory disorders such as in the treatment of rheumatoid arthritis, uveitis, Inflammatory bowel disease, ulcerative colitis, dermatitis, bronchitis, meningitis, sinusitis, periodontitis etc. In inflammatory process various mechanisms are involved4.
Symptoms:
?It is pain in muscles and joints.
?The person has fatigue.
?It was difficult to sleep.
?Depression and anxiety.
?There are Digestive problems.
?There are frequent infections.
Causes:
Typical causes include:
• Insufficient physical activity.
• Prolonged tension.
• Obesity is defined as having a BMI of 30 or higher, particularly if the additional weight includes visceral fat, which is found deep within the abdomen.
• Dysbiosis, or an imbalance between beneficial and detrimental microbes in your gut.
• Consistently consuming inflammatory foods, such as those high in trans-fat or salt
• Sleep and circadian rhythm disturbances.
• Toxin exposure, such as exposure to industrial chemicals, hazardous waste, and air pollution.
• Making use of tobacco products.
• Consistently consuming excessive amounts of alcohol.
Risk Factors of Inflammation:
Types of Inflammation
Sakshi Gaikwad*, Vikram Sarukh, Gauri Paithankar, Pooja Lasure, Ramdas Darade, A Review of Anti-Inflammatory Herbs for Wound Healing: Traditional Knowledge and Insights Applications, Int. J. Sci. R. Tech., 2025, 2 (8), 147-165. https://doi.org/10.5281/zenodo.16811628
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10.5281/zenodo.16811628
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