View Article

Abstract

It is a fastgrowing annual vine that produces large, oblong fruits covered in a waxy, ashlike coating, which contributes to its common name. The fruit is rich in moisture, low in calories, and packed with essential nutrients, making it an important component of traditional diets and health remedies. Ash gourd has been recognized for its diverse pharmacological properties, including antioxidant, anti-inflammatory, diuretic, antimicrobial, and neuroprotective effects. It is a prominent Ingredient in Ayurveda and other traditional medicine systems, where it is used to treat ailments such as gastric ulcers, respiratory disorders, and metabolic imbalances. Its seeds, pulp, and rind have all demonstrated therapeutic potential. In agriculture, Benincasa hispida is valued for its adaptability, long shelf life, and resistance to pests, making it a viable crop in both subsistence and commercial farming systems. Ongoing research continues to explore its bioactive compounds and potential applications in functional foods and pharmaceuticals.This study/project aims to explore the botanical characteristics, nutritional composition, medicinal properties, and economic significance of Benincasa hispida, contributing to a deeper understanding of its role in sustainable agriculture and natural healthcare.

Keywords

Benincasa Hispida, Pharmacognostical, Phytochemical Evaluation

Introduction

Benincasa hispida (Thunb.) Cogn., commonly referred to as winter melon, ash gourd, white gourd, or wax gourd, is a valuable plant both economically and nutritionally, belonging to the Cucurbitaceae family. It is an annual climbing vine extensively grown in tropical and subtropical regions of Asia, particularly in countries such as India, China, Indonesia, and the Philippines. The plant features coarse, hairy stems, broad palmately lobed leaves, and yellow unisexual flowers that emerge from the leaf axils. Its fruits are generally large, fleshy, and cylindrical, usually measuring 40–60 cm in length, though they may reach up to 80 cm in some cases. Young fruits are covered with fine hairs that disappear upon maturity, leaving a thick whitish waxy layer, which significantly prolongs their storage life [1]. The fruit has a subtle, cucumber-like flavor and contains around 96% water, making it a hydrating and low-calorie food choice. It is valued not only for its culinary versatility but also for its nutritional composition, providing carbohydrates, proteins, dietary fiber, vitamins (notably vitamin C and certain B-complex vitamins), as well as minerals like calcium, iron, and phosphorus. Due to its mild taste, B. hispida readily absorbs spices and seasonings, making it suitable for a variety of dishes. In Indian cuisine, it is used in curries, sweets (such as petha), pickles, and stews, while in Chinese and Southeast Asian cooking, it is a common ingredient in soups, stir-fries, and sweet beverages like winter melon tea. Its thick waxy coating extends its shelf life, enhancing its importance in trade and long-term storage. Beyond its nutritional benefits, Benincasa hispida has long been an important component of traditional medicine for managing various health conditions. In traditional Chinese medicine, it is commonly recommended for alleviating heat, reducing inflammation, and addressing ailments related to edema and phlegm [2]. Different parts of the plant, including the seeds, rind, and leaves, are also employed in ethnomedicine for their wide range of therapeutic properties, such as anthelmintic, anti-inflammatory, and antiseptic activities. Recent pharmacological research has validated many of the traditional medicinal applications of B. hispida. Experimental studies have shown that its extracts possess antioxidant, anti-ulcer, anti-inflammatory, antimicrobial, neuroprotective, and anticancer activities. Several bioactive compounds have been identified, including flavonoids, triterpenes, glycosides, phenolic acids, sterols, and essential oils, which are largely responsible for its therapeutic potential. Additionally, because of its highwater content and low caloric value, the fruit is recognized in modern nutrition as a functional food that supports weight management and promotes metabolic health [3].

Reference

  1. Wikipedia – An online article describing the wax gourd (Benincasa hispida), its characteristics, and general uses.
  2. Morton JF – Fruits of Warm Climates (1987), Miami: A comprehensive book covering various fruits that thrive in tropical and subtropical regions.
  3. Impactfactor.org – A 2023 paper in the International Journal of Pharmaceutical Quality Assurance (14[2]:207–215) presenting the nutritional value and key phytochemicals of Benincasa hispida.
  4. Dr. Axe – A web resource detailing the nutritional profile and health-promoting properties of winter melon.
  5. USDA FoodData Central – An official database offering the full nutrient composition of winter melon.
  6. The Spruce Eats – An online guide highlighting winter melon’s culinary applications and basic background information.
  7. Sharma PV – Dravyaguna Vijnana, Vol. II (2005), Varanasi: A text on the medicinal uses of vegetable-based herbal remedies in traditional Indian medicine.
  8. Chen JK & Chen TT – Chinese Medical Herbology and Pharmacology (2004), City of Industry: A detailed reference on Chinese herbal medicine and pharmacological practices.
  9. Plants for A Future (PFAF) – An online database entry describing the botanical features and potential uses of Benincasa hispida.
  10. Sonawane RD et al. – A review in Pharmacognosy Reviews (2021;15[30]:122–130) discussing the pharmacological activities of Benincasa hispida.
  11. Singh A et al. – An article in Pharmacognosy Journal (2020;12[6]:1238–1246) covering the phytochemistry and medicinal potential of Benincasa hispida.
  12. World Health Organization – Diet, Nutrition and the Prevention of Chronic Diseases (Technical Report Series 916; 2003), a report outlining how diet and nutrition can help prevent long-term illnesses.
  13. Kirtikar KR, Basu BD. Indian Medicinal Plants, Vol. II. Dehradun: International Book Distributors; 1991.
  14. Sonawane RD, et al. “Pollination and Fruit Set in Cucurbit Crops: A Review.” Pharmacognosy Reviews. 2021;15(30):122–130.
  15. Nadkarni KM. Indian Materia Medica. Mumbai: Popular Prakashan; 2002.
  16. Peter KV. Underutilized and Underexploited Horticultural Crops. New Delhi: New India Publishing Agency; 2007.
  17. Grubben GJH, Denton OA. Plant Resources of Tropical Africa 2: Vegetables. PROTA Foundation, Wageningen, Netherlands; 2004.
  18. Rai N, Pandey AK, Singh M. “Genetic Improvement and Production of Ash Gourd (Benincasa hispida).” Vegetable Science. 2016;43(2):123–129.
  19. Ravindran PN, Mathew G, Nirmal Babu K. The Encyclopedia of Herbs and Spices. Wallingford (UK): CABI Publishing; 2017.
  20. Rai N, Yadav DS. Advances in Vegetable Production. New Delhi: Research Book Centre; 2005.
  21. Choudhury B. Vegetable Crops. New Delhi: National Book Trust, India; 2015.
  22. Grubben GJH, Denton OA. Plant Resources of Tropical Africa 2: Vegetables. Wageningen, Netherlands: PROTA Foundation; 2004. (duplicate citation retained if needed).
  23. Nayar NM, More TA. Cucurbits. New Delhi: Oxford & IBH Publishing; 1998.
  24. Kumar R, Sharma S. “Agro-botanical Description and Utilization of Ash Gourd (Benincasa hispida).” International Journal of Vegetable Science. 2014;20(3):210–220.
  25. Khandelwal KR. Practical Pharmacognosy: Techniques and Experiments. 19th ed. Pune: Nirali Prakashan; 2008.
  26. Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy. 45th ed. Pune: Nirali Prakashan; 2010.
  27. Dey PM, Harborne JB. Plant Biochemistry. San Diego: Academic Press; 1997.
  28. Government of India, Ministry of Health and Family Welfare. The Ayurvedic Pharmacopoeia of India, Vol. I, Part I. New Delhi: Department of Indian Systems of Medicine and Homoeopathy; 2001.
  29. Singh S. “Pharmacological Update on Benincasa hispida (Thunb.).” Journal of Herbal Medicine. 2024.
  30. Islam MT, et al. “A Literature-Based Update on Benincasa hispida (Thunb.).” EvidenceBased Complementary and Alternative Medicine. 2021; Article ID 6349041.
  31. Chaitali W, et al. “A Concise Review on Benincasa hispida (Thunb.) Cogn.” International Journal of Health Sciences. 2022;6(1):123–130.
  32. Abood Al-Saadi SA, Abass KS. “Benincasa hispida as an Antioxidant of Possible Physiological Significance: A Comparative Review.” Research Journal of Pharmacy and Technology. 2020;13(8):3929–3934.
  33. Harborne JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. 3rd ed. Springer; 1998.
  34. Kanase M, et al. “Phytochemical and Pharmacological Profile of Benincasa hispida.” Pharmacognosy Reviews. 2025;19(2):55–63.
  35. Zhang M, et al. “Traditional Uses, Phytochemistry and Pharmacology of Benincasa hispida.” Chinese Herbal Medicines. 2023;15(2):134–148.
  36. Chaitali W, et al. “Antioxidant, Anticancer and Central Nervous System Activities of Benincasa hispida.” Research Journal of Pharmacognosy and Phytochemistry. 2022;14(2):97– 104.
  37. Impact Factor Journal. “Pharmacological Effects of Benincasa hispida Seed Extracts: CNS and Anticonvulsant Investigations.” International Journal of Pharmaceutical Quality Assurance. 2023;14(2):210–217.
  38. Singh S. “Pharmacological Update on Benincasa hispida (Thunb.).” Journal of Herbal Medicine. 2024.
  39. Islam MT, et al. “A Literature-Based Update on Benincasa hispida (Thunb.).” EvidenceBased Complementary and Alternative Medicine. 2021; Article ID 6349041.
  40. Chaitali W, et al. “A Concise Review on Benincasa hispida (Thunb.) Cogn.” International Journal of Health Sciences. 2022;6(1):123–130.
  41. Anonymous. “A Review on Nutritional and Industrial Applications of Benincasa hispida.” International Journal of Pharmacognosy and Phytochemistry. 2022;14(2):150–158.
  42. Kokate CK, Purohit AP, Gokhale SB. Pharmacognosy. Widely used Indian university textbook; latest Indian edition (commonly cited 45th ed., Nirali Prakashan).
  43. Evans WC. Trease and Evans’ Pharmacognosy. London: Elsevier/Churchill Livingstone; latest available edition.
  44. Patel DK, Patel K, Tahilyani V. “Benincasa hispida: Review of Phytochemical Constituents and Pharmacological Activities.” Asian Pacific Journal of Tropical Medicine.
  45. Maurya A, et al. “Phytochemical and Pharmacological Profile of Benincasa hispida.” International Journal of Pharmaceutical Sciences Review and Research.
  46. Abood Al-Saadi SA, Abass KS. “Benincasa hispida as a Potential Physiological Antioxidant: A Comparative Review.” Research Journal of Pharmacy and Technology. 2020;13(8):3929– 3934.
  47. Kanase M, et al. “Phytochemical Constituents and Pharmacological Activities of Benincasa hispida.” Pharmacognosy Reviews. 2025;19(2):55–63.
  48. Zhang M, et al. “Traditional Uses, Phytochemistry, and Pharmacological Insights on Benincasa hispida.” Chinese Herbal Medicines. 2023;15(2):134–148.
  49. Chaitali W, et al. “Antioxidant, Anticancer, and Central Nervous System Effects of Benincasa hispida.” Research Journal of Pharmacognosy and Phytochemistry. 2022;14(2):97– 104.
  50. Harborne JB. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. 3rd ed. Berlin: Springer; 1998.
  51. Impact Factor Journal. “Pharmacological Effects of Benincasa hispida Seed Extracts: Central Nervous System and Anticonvulsant Studies.” International Journal of Pharmaceutical Quality Assurance. 2023;14(2):210–217.
  52. Wikipedia. “Wax Gourd (Benincasa           hispida).”         Available         from: https://en.wikipedia.org/wiki/Wax_gourd
  53. McGregor SE. Insect Pollination of Cultivated Crop Plants. USDA Agriculture Handbook No. 496; 1976.
  54. Nath P, et al. “Pollination Biology of Cucurbitaceous Vegetables.” Journal of Applied Horticulture. [Year, volume, and page numbers to be added if available].
  55. Sharma PV. Dravyaguna Vijnana (Materia Medica – Vegetable Drugs). Vol. II. Varanasi: Chaukhambha Bharati Academy; 2005.
  56. Esau K. Plant Anatomy. 2nd ed. New York: John Wiley & Sons; 1977.
  57. Singh A, et al. “Phytochemical and Pharmacological Aspects of Benincasa hispida.” Pharmacognosy Journal. 2020;12(6):1238–1246.
  58. Zin CAJC M, Ishak WRW, Khan NAK, et al. “Acute and Sub-chronic Toxicity Assessment of Benincasa hispida Fruit Extract in Rodent Models.” International Journal of Health Sciences (Qassim). 2024;18(2):213–219.
  59. Kirtikar KR, Basu BD. Indian Medicinal Plants. Vol. II. Dehradun: International Book Distributors; 1991.
  60. Sharma PV. Dravyaguna Vijnana (Materia Medica – Vegetable Drugs). Vol. II. Varanasi: Chaukhambha Bharati Academy; 2005.
  61. Chen JK, Chen TT. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press; 2004.
  62. Singh A, et al. Phytochemical and pharmacological characteristics of Benincasa hispida. Pharmacognosy Journal. 2020;12(6):1238–1246.
  63. Sonawane RD, et al. Pharmacological potential of Benincasa hispida: a review. Pharmacognosy Reviews. 2021;15(30):122–130.
  64. Rahman MA, et al. Phytochemical screening and medicinal properties of Benincasa hispida leaves. Journal of Ethnopharmacology. 2019; 232:211–220.
  65. Kirtikar KR, Basu BD. Indian Medicinal Plants. Vol. II. Dehradun: International Book Distributors; 1991.
  66. Sharma PV. Dravyaguna Vijnana (Materia Medica – Vegetable Drugs). Vol. II. Varanasi: Chaukhambha Bharati Academy; 2005.
  67. Chen JK, Chen TT. Chinese Medical Herbology and Pharmacology. City of Industry, CA: Art of Medicine Press; 2004.
  68. Singh A, et al. Phytochemical and pharmacological characteristics of Benincasa hispida. Pharmacognosy Journal. 2020;12(6):1238–1246.
  69. Sonawane RD, et al. Pharmacological potential of Benincasa hispida: a review. Pharmacognosy Reviews. 2021;15(30):122–130.
  70. Rahman MA, et al. Phytochemical screening and medicinal properties of Benincasa hispida leaves. Journal of Ethnopharmacology. 2019; 232:211–220.

Photo
F. Pincy Mol
Corresponding author

Sun College of Pharmacy and Research Center

Photo
Madhankumar R.
Co-author

Sun College of Pharmacy and Research Center

Photo
Harish S.
Co-author

Sun College of Pharmacy and Research Center

Photo
Sowmiya J. S.
Co-author

Sun College of Pharmacy and Research Center

Photo
Reshma R. Nath
Co-author

Sun College of Pharmacy and Research Center

Photo
Asha A. S.
Co-author

Sun College of Pharmacy and Research Center

F. Pincy Mol*, Madhankumar R., Harish S., Reshma R. Nath, Sowmiya J. S., Asha A. S., Pharmacognostical and Phytochemical Evaluation of Benincasa Hispida, Int. J. Sci. R. Tech., 2026, 3 (1), 236-250. https://doi.org/10.5281/zenodo.18298642

Related Articles
Analyze the Impact of Fintech on Traditional Banking...
Dr. R. Chandhrasekaran , Mathumitha S., ...
Immuno-Oncology in Cancer Therapy: Mechanistic Insights, Clinical Applications, ...
Tejaswini Bhavar, Sonal Bhatkar , Rutuja Rathod, Sumit Kolse , Prajkta Mahajan , ...
Formulation and Evaluation of Herbal Ointment from Neem and Turmeric Extract...
Anil Panchal, Abdul Kalam Abdul Jabbar Nadaf, Vishal Madankar, MD Tanvir Hamid Karajagikar, ...