View Article

Abstract

The rapid evolution of technology has revolutionized pharmacy practice, with robotics and artificial intelligence (AI) emerging as powerful tools in modern pharmacy automation. Robotics has transformed medication dispensing, compounding, and inventory management by enhancing accuracy, efficiency, and safety. Simultaneously, AI systems have enabled intelligent clinical decision support, drug interaction prediction, personalized dosing, and data-driven patient care. Together, these technologies are reshaping hospital, community, and clinical pharmacy workflows, reducing human error, and allowing pharmacists to focus on patient-centered services. Despite challenges related to cost, integration, and ethics, the synergy of robotics and AI holds significant promise for improving healthcare outcomes and operational excellence in pharmacy. This review explores current advancements, applications, limitations, and future directions of robotics and AI in pharmacy automation.

Keywords

Robotics in Pharmacy, Pharmacy Automation, Artificial Intelligence, Smart Pharmacy

Introduction

The global healthcare system is under increasing pressure to deliver accurate, efficient, and cost-effective services. In this context, pharmacy automation, supported by robotic systems and AI-driven analytics, is gaining momentum. These technologies address key challenges such as medication errors, inventory mismanagement, and pharmacist burnout, allowing pharmacists to focus more on clinical and patient-centered care. Pharmacy automation refers to the use of technology—including robotic systems, software solutions, and artificial intelligence (AI)—to perform and optimize tasks in pharmaceutical operations such as dispensing, compounding, inventory management, and medication tracking. The primary goal is to enhance accuracy, reduce medication errors, improve workflow efficiency, and allow pharmacists to focus more on clinical care and patient counseling. As the global demand for healthcare services grows, the pressure on pharmacy systems to deliver safe, fast, and cost-effective medication management has intensified. Automation has emerged as a key strategy to address these challenges by minimizing human error, ensuring proper dosage and labeling, and improving overall pharmaceutical service delivery (1). Automated pharmacy systems range from unit dose dispensing robots and automated storage systems to intelligent IV compounding units and robotic prescription counters. These systems have been shown to reduce medication errors by up to 50% in hospital settings (2). Furthermore, with the integration of AI algorithms, pharmacies can now support predictive analytics, clinical decision support, and personalized medication therapy, creating a transformative shift toward smart and data-driven pharmacy practice (3).

Evolution of Pharmacy Automation

Pharmacy automation has undergone a significant transformation over the past two decades — evolving from simple pill counters and barcode systems to highly intelligent robotic and AI-integrated platforms.

 Key Milestones:

  • Early 2000s: Introduction of automated dispensing cabinets (e.g., Pyxis, Omnicell) in hospital settings.
  • 2010s: Widespread use of robotic arms for medication dispensing, IV admixture compounding, and packaging (e.g., RIVA, ScriptPro).
  • 2020s and Beyond: Integration of AI, machine learning, predictive analytics, and cloud-based systems, enabling “smart pharmacies” that are capable of clinical decision support and real-time inventory optimization (4)

Why is Pharmacy Automation Needed?

The need for pharmacy automation is driven by several systemic, clinical, and operational challenges:

a. Reducing Medication Errors

  • Medication errors affect millions of patients globally and are a leading cause of preventable harm.
  • Automation improves accuracy in drug dispensing and labeling by minimizing human intervention.

b. Improving Workflow Efficiency

  • Manual prescription filling is time-consuming and error-prone.
  • Automated systems can handle thousands of prescriptions per day, freeing pharmacists to focus on clinical roles and patient counseling

c. Supporting Clinical Decision-Making

  • AI integration allows for real-time alerts about drug interactions, dose adjustments, and therapy optimization.
  • Enhances patient safety and treatment efficacy through data-driven insights.

d. Managing Inventory and Supply Chain (5)

  • Automated storage and retrieval systems (ASRS) ensure accurate stock control, reduce waste, and streamline the pharmaceutical supply chain.
  • Especially valuable in high-volume hospital pharmacies and national-level vaccine distribution.

Applications of AI and Robotics in Pharmaceutical Sciences:

It’s not only in pharma manufacturing that robots are taking a deep dive.  Packing, labeling, and quality control are done by automated systems with higher throughput and fewer human mistakes. Such automation increases overall production efficiency and helps to meet high-level regulatory requirements. Also, robots may cooperate with human workers, providing more power and accuracy in difficult processes [6,7]. The individualization of medicine is also supported by AI applications that use clinical evidence to inform treatment decision-making.  AI, for example, can read a patient’s medical history and genomic information and recommend the most efficient regimens that will fit the patient’s profile. Such personalization not only makes treatment more effective but also increases patients’ satisfaction and compliance with therapy [8, 9]. Overall, AI and robotics used in pharmaceutical science improve drug discovery, personalized medicine, and pharmaceutical manufacturing efficiency that ultimately leads to improved patient outcomes and care. 

Reference

  1. Pedersen, C.A., Schneider, P.J., & Scheckelhoff, D.J. (2018). ASHP national survey of pharmacy practice in hospital settings: Dispensing and administration. American Journal of Health-System Pharmacy, 75(16), 1203–1226.
  2. Aburas, W.I., & Alshammari, T.M. (2021). Pharmacy automation and its impact on patient safety and workflow. Healthcare, 9(5), 539.
  3. Gupta, R., Sharma, P., & Verma, N. (2021). Artificial intelligence and pharmacy: A review of current status and future prospects. Research in Social and Administrative Pharmacy, 17(1), 132–139.
  4. Li, J., Shah, M., & Qu, M. (2020). Smart pharmacy: Applications of robotics and artificial intelligence in pharmacy practice. Frontiers in Pharmacology, 11, 1198.
  5. Maiti, B., & Kundu, A. (2022). Automation in hospital pharmacy: The future of medication management. Int J Health Sci, 6(S4), 3222–3231.
  6. Swapna, B.  V., Shetty, S., Shetty, M., & Shetty, S.  S. (2024). Smart science: How artificial intelligence is revolutionizing pharmaceutical medicine.  Acta Marisiensis - Seria Medica, 70(1), 8–15.
  7. Markus, B., C, G. C., Andreas, K., Arkadij, K., Stefan, L., Gustav, O., Elina, S., & Radka, S. (2023). Accelerating Biocatalysis Discovery with Machine Learning:  A Paradigm Shift in Enzyme Engineering, Discovery, and Design. ACS Catalysis, 13(21), 14454–14469.
  8. T, M. K., B, P., Nunavath, R. S., & Nagappan, K. (2024). Future of pharmaceutical Industry: Role of artificial intelligence, automation, and robotics. Journal of Pharmacology and Pharmacotherapeutics, 15(2), 142–152.
  9. Henstock, P. (2020). Artificial intelligence in pharma: Positive trends but more investment needed to drive a transformation.  Archives of Pharmacology and Therapeutics, 2(2),  24–28. https://doi.org/10.33696/pharmacol.2.017
  10. Gausepohl, T. (2022). Automation in Pharmaceutical Packaging: Trends and Applications. Pharmaceutical Engineering, ISPE.
  11. Madsen, M. et al. (2020). “Robotic Systems in Aseptic Processing.” Journal of Pharmaceutical Innovation, 15(3), 251–258.
  12. Pharmaceutical Manufacturing. Smarter, Faster, Safer: Robotics in Pharma Packaging. Retrieved from//www.pharmamanufacturing.com/articles/2021/robotics-in-pharma-packaging/(2021).
  13. Sharma, A., & Pai, R. M. (2021). “Serialization in Pharma: Challenges and Robotic Solutions.” Journal of Pharmaceutical Sciences and Research, 13(9), 454–458.
  14. Dixon, B. End-of-Line Packaging Automation: Boosting Output and Accuracy. European Pharmaceutical Manufacturer, (2019).
  15. Deep Genomics. Programming RNA Therapies Any Gene, Any Genetic Condition. [cited 2022 13 June];
  16. Shampo, M.A. and Kyle R.A., J. Craig Venter--The Human Genome Project. Mayo Clinic proceedings, 2011. 86(4): p. e26-e27
  17. Muhammad Ahmer Raza, Shireen Aziz , Misbah Noreen,  Amna Saeed , Irfan Anjum , Mudassar Ahmed , Shahid Masood Raza , Artificial Intelligence (AI) in Pharmacy: An Overview of Innovations, Innov Pharm. 2022 Dec 12;13(2):10.24926/iip.v13i2.4839.
  18. L. Zhang, H. Zhang, H. Ai, et al. Applications of machine learning methods in drug toxicity prediction Curr Top Med Chem, 18 (12) (2018), pp. 987-997, 
  19. H. Yang, L. Sun, W. Li, G. Liu, Y. Tang In silico prediction of chemical toxicity for drug design using machine learning methods and structural alerts Front Chem, 6 (2018), p. 30,
  20. J.B. Mitchell, Artificial intelligence in pharmaceutical research and development Future Med Chem, 10 (13) (2018), pp. 1529-1531.
  21. V.L. Gaikwad, M.S. Bhatia, I. Singhvi, Effect of polymeric properties on physical characteristics of fast disintegrating ibuprofen tablets: a statistical approach, Pharm Lett, 5 (3) (2013), pp. 140-147
  22. V.L. Gaikwad, A.J. Kasabe, A.S. Kulkarni, N.M. Bhatia, M.S. Bhatia, Quantitative structure–property relationship approach in formulation development: an overview Pharm SciTech, 20 (2019), p. 268
  23. V.L. Gaikwad, M.S. Bhatia, I. Singhvi, Statistical modeling of physical characteristics of fast disintegrating glipizide tablets using polymeric properties Int J Pharm Technol, 5 (2) (2013), pp. 5586-5601.

Photo
Dipak Bhingardeve
Corresponding author

Shree Santkrupa College of Pharmacy Ghogaon, Tal-Karad Dist-Satara, MH, India,415111

Photo
Yuvraj Amale
Co-author

Shree Santkrupa College of Pharmacy Ghogaon, Tal-Karad Dist-Satara, MH, India,415111

Photo
Atul Kadam
Co-author

Shree Santkrupa College of Pharmacy Ghogaon, Tal-Karad Dist-Satara, MH, India,415111

Photo
Amit Atugade
Co-author

Shree Santkrupa College of Pharmacy Ghogaon, Tal-Karad Dist-Satara, MH, India,415111

Photo
Sanket Patil
Co-author

Shree Santkrupa College of Pharmacy Ghogaon, Tal-Karad Dist-Satara, MH, India,415111

Yuvraj Amale, Atul Kadam, Amit Atugade, Sanket Patil, Dipak Bhingardeve*, Transforming Pharmacy Automation: The Role of Robotics and Artificial Intelligence, Int. J. Sci. R. Tech., 2025, 2 (10), 389-395. https://doi.org/10.5281/zenodo.17443152

More related articles
Sustainable Urban Landscape Design - Concept, Purp...
Purvi Dabhi, Isha Pandya, Bharat Maitreya, ...
Comprehensive Pharmacological Study of Cannabis Sa...
Akshay Wagh, Kunal Kothawade, Shivshankar Ambhore, Dr. Avinash Da...
Drug Use Evaluation of Osteoarthritis...
Jayprakash, Kavita Lovanshi, Shailesh Jain, Rita Mourya, Aashish Choudhory, ...
More related articles
Comprehensive Pharmacological Study of Cannabis Sativa Plant...
Akshay Wagh, Kunal Kothawade, Shivshankar Ambhore, Dr. Avinash Darekar , ...