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Abstract

This study details the formulation and evaluation of a lip balm enriched with Mangifera indica (mango) leaf extract, targeting enhanced antioxidant activity for improved lip care. Mangifera indica leaves are recognized for their high content of phenolic compounds and flavonoids, which contribute significant antioxidant potential. The extract was obtained through ethanol maceration and incorporated into a natural lip balm base. The prepared formulations were assessed for physicochemical parameters including pH, spreadability, melting point, and revealing that the lip balm containing Mangifera indica leaf extract exhibited superior antioxidant activity. Organoleptic evaluation confirmed acceptable texture, aroma, and appearance, while skin irritation tests indicated good tolerability. The findings demonstrate that incorporating Mangifera indica leaf extract into lip balm not only enhances its antioxidant properties but also maintains desirable cosmetic and safety profiles. This approach supports the development of natural, functional lip care products with added therapeutic benefits for lip protection and nourishment.

Keywords

Mangifera indica, lip balm, antioxidant activity, natural extracts, topical formulation, phenolic compounds

Introduction

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Lips are soft, movable, and highly sensitive structures located at the opening of the mouth. The skin on the lips is very thin and does not have oil glands, which makes them dry and cracked easily, especially in cold or dry weather. Because of this, lips need special care to stay soft and healthy. Their delicate nature requires regular care and protection, especially from harsh weather conditions, dehydration, and UV exposure. Proper lip care is essential not only for maintaining appearance but also for ensuring comfort and preventing infections or inflammation. They help us talk, eat, smile, and show emotions.  Using lip care products like lip balm helps protect the lips from dryness and damage. Natural ingredients, such as mango leaf extract, can help heal and protect the lips because they have antioxidant and anti-inflammatory properties.

  1. ANATOMY OF LIPS: -

Reference

  1. Anisa, H., Sukmawardani, Y., & Windayani, N. (2019, December). A simple formulation of lip balm using carrot extract as a natural coloring agent. In Journal of Physics: Conference Series (Vol. 1402, No. 5, p. 055070). IOP Publishing.
  2. Azmin, S. N. H. M., Sulaiman, N. S., Yosri, N. A., Nor, M., & Abdullah, P. (2021). Stability analysis of carrot-based natural moisturising lip balm. Chemical Engineering Transactions.
  3. Gadge, S. S., Sonare, P. V., & Masram, P. (2023). Formulation and evaluation of herbal lipstick from the beetroot-a natural coloring matter. J Pharm Tech, 14, 15-19.
  4. Greenberg, S. A., Schlosser, B. J., & Mirowski, G. W. (2017). Diseases of the lips. Clinics in Dermatology, 35(5), e1-e14.
  5. Itoh, K., Matsukawa, T., Okamoto, M., Minami, K., Tomohiro, N., Shimizu, K., ... & Shigeoka, S. (2020). In vitro antioxidant activity of Mangifera indica leaf extracts. Journal of Plant Studies; Vol, 9(2).
  6.  Kadu, M., Vishwasrao, S., & Singh, S. (2015). Review on natural lip balm. International Journal of Research in Cosmetic Science, 5(1), 1-7.
  7. Khumpook, T., Saenphet, S., Tragoolpua, Y., & Saenphet, K. (2019). Anti-inflammatory and antioxidant activity of Thai mango (Mangifera indica Linn.) leaf extracts. Comparative Clinical Pathology, 28, 157-164.
  8. Lote, S., Dandekar, M., Dandekar, P., Chamat, S., & Bhanuse, R. (2024, December). Formulation and evaluation of herbal lip balm. In AIP Conference Proceedings (Vol. 3188, No. 1). AIP Publishing.
  9. Piccinin, M. A., & Zito, P. M. (2018). Anatomy, head and neck, lips.
  10. Pirca-Palomino, M., Malange, Y. I., Ramos-Escudero, F., Muñoz, A. M., & Cancino-Chávez, K. (2024). Antioxidant Properties, Texture and Sensory Quality of Sliced Bread Enriched with Leaf Powder from Mango (Mangifera indica). Polish Journal of Food and Nutrition Sciences, 74(4), 313-322.
  11. Sankar, A., Sunny, M., Mathews, M. M., & Joseph, D. (2025). Formulation and Evaluation of Herbal Lipbalm for the Treatment of Cheilitis. Journal of Pharmaceutical Innovation, 20(3), 1-13.
  12. Sutthiboonyapan, P., Sriratanasak, N., Innets, B., Angkanaporn, N., Suntornchot, P., Panyain, W., ... & Chanvorachote, P. (2025). A Randomized Double?Blind Controlled Evaluation of the Therapeutic Benefits of an Herbal Lip Hydrant. Journal of Cosmetic Dermatology, 24(3), e70041.
  13. Veludurthi, P. A., & Vadaga, A. K. (2024). A Comprehensive Review of Formulations, Ingredients, Advances, and Future Perspectives in Lipcare Cosmetics. Journal of Pharma Insights and Research, 2(3), 123-128.
  14. Zugerman, C. (1986). The lips: anatomy and differential diagnosis. Cutis, 38(2), 116-120.

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Vishakha Nagare
Corresponding author

Department of Pharmaceutics "Krantiveer Vasantrao Narayanrao Naik Shikshan Prasarak Sanstha's Institute of Pharmaceutical Education and Research", Nashik – 422002, Maharashtra, India

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Priyanka Koli
Co-author

Department of Pharmaceutics "Krantiveer Vasantrao Narayanrao Naik Shikshan Prasarak Sanstha's Institute of Pharmaceutical Education and Research", Nashik – 422002, Maharashtra, India

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Ghanshyam Rathod
Co-author

TVES Hon'ble Loksevak Madhukarrao Chaudhari College Of Pharmacy, Faizpur

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Shivani Pohekar
Co-author

TVES Hon'ble Loksevak Madhukarao Chaudhari College of Pharmacy Faizpur

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Dr. Avinash Darekar
Co-author

Department of Pharmaceutics "Krantiveer Vasantrao Narayanrao Naik Shikshan Prasarak Sanstha's Institute of Pharmaceutical Education and Research", Nashik – 422002, Maharashtra, India

Vishakha Nagare*, Priyanka Koli, Ghanshyam Rathod, Shivani Pohekar, Dr. Avinash Darekar, Formulation and Evaluation of Mangifera Indica Leaf Extract Lip Balm for Enhanced Antioxidant Activity, Int. J. Sci. R. Tech., 2025, 2 (7), 65-74. https://doi.org/10.5281/zenodo.15801278

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